Background: Due to the resurgence of pertussis, many countries have revised the pertussis
immunization schedules and recommended booster doses of pertussis component vaccine …

Background. Acellular pertussis (aP) and whole-cell (wP) pertussis vaccines are presumed
to have similar short-term (< 3 years after completion of the primary series) efficacy …

BACKGROUND: Increasing incidence of pertussis in adolescents and adults has stimulated
the development of safe and immunogenic acellular pertussis vaccines for booster …

Objective Severe pertussis infection has been reported in infants before receiving routine
immunization series. This problem could be solved by vaccinating mothers during …

Objective. This case-control study investigated the protective efficacy against pertussis of
three doses of a two-component acellular pertussis vaccine (manufactured by Biken in …

Background. The recent introduction of acellular pertussis vaccines (Pa) offers the possibility
of booster doses in older children and adults. This can be conveniently accomplished by …

Objective: To assess the efficacy and safety of whole-cell and acellular pertussis vaccines
administered to children singly or within diphtheria, tetanus and pertussis (DTP) vaccines …

The recent increase of pertussis in young adults in Japan is hypothesized to be due in part
to waning protection from the acellular pertussis vaccine. While a booster immunization may …

Background Acellular pertussis vaccine studies postulate that waning protection, particularly
after the adolescent booster, is a major contributor to the increasing US pertussis incidence …

Pertussis is an important cause of morbidity and mortality, and its incidence has been
increasing in adolescents and adults over the past two decades. Waning immunity in …