Multivalent gold nanoparticle–peptide conjugates for targeting intracellular bacterial infections
Although nanoparticle-tagged antimicrobal peptides have gained considerable importance
in recent years, their structure–function correlation has not yet been explored. Here, we have …
in recent years, their structure–function correlation has not yet been explored. Here, we have …
Small synthetic peptides bioconjugated to hybrid gold nanoparticles destroy potentially deadly bacteria at submicromolar concentrations
G Palmieri, R Tatè, M Gogliettino… - Bioconjugate …, 2018 - ACS Publications
Synthetic antibacterial peptides are advanced weapons that scientists design and produce
to confront current threats of harmful and mortal pathogens, which could affect humans in …
to confront current threats of harmful and mortal pathogens, which could affect humans in …
Gold nanoparticle-DNA aptamer conjugate-assisted delivery of antimicrobial peptide effectively eliminates intracellular Salmonella enterica serovar Typhimurium
JH Yeom, B Lee, D Kim, J Lee, S Kim, J Bae, Y Park… - Biomaterials, 2016 - Elsevier
Antimicrobial peptides (AMPs) are a promising new class of antibacterial compounds.
However, their applications in the treatment of intracellular pathogenic bacteria have been …
However, their applications in the treatment of intracellular pathogenic bacteria have been …
A peptide-nanoparticle system with improved efficacy against multidrug resistant bacteria
The recent rise of multidrug resistant microbial strains requires development of new and
novel therapeutic alternatives. In this study, we present a novel antibacterial system that …
novel therapeutic alternatives. In this study, we present a novel antibacterial system that …
Size-controlled synthesis of gold nanoparticles tethering antimicrobial peptides with potent broad-spectrum antimicrobial and antibiofilm activities
U Rajchakit, S Lamba, K Wang, N Lyons… - Molecular …, 2024 - ACS Publications
New antimicrobials are urgently needed to combat the rising global health concern of
antibiotic resistance. Antimicrobial peptides (AMPs) are one of the leading candidates as …
antibiotic resistance. Antimicrobial peptides (AMPs) are one of the leading candidates as …
One-step synthesis of high-density peptide-conjugated gold nanoparticles with antimicrobial efficacy in a systemic infection model
The increase in antibiotic drug resistance and the low number of new antibacterial drugs
approved in the last few decades requires the development of new antimicrobial strategies …
approved in the last few decades requires the development of new antimicrobial strategies …
Combining antimicrobial peptides with nanotechnology: an emerging field in theranostics
The emergence of multidrug-resistant pathogens and their rapid adaptation against new
antibiotics is a major challenge for scientists and medical professionals. Different …
antibiotics is a major challenge for scientists and medical professionals. Different …
Insights into cell penetrating peptide conjugated gold nanoparticles for internalization into bacterial cells
Gold nanoparticles (AuNPs) functionalized with different biomolecules find extensive
application in therapy, clinical diagnosis and biomedical imaging. Herein, two derivatives of …
application in therapy, clinical diagnosis and biomedical imaging. Herein, two derivatives of …
Orientational Nanoconjugation with Gold Endows Marked Antimicrobial Potential and Drugability of Ultrashort Dipeptides
Z Zhang, Y Chen, J Gao, M Yang, D Zhang, L Wang… - Nano Letters, 2023 - ACS Publications
Antibiotic resistance is a global threat. Antimicrobial peptides (AMPs) are highly desirable to
treat multidrug-resistant pathogen infection. However, few AMPs are clinically available, due …
treat multidrug-resistant pathogen infection. However, few AMPs are clinically available, due …
The membrane-targeting mechanism of host defense peptides inspiring the design of polypeptide-conjugated gold nanoparticles exhibiting effective antibacterial …
Multidrug-resistant bacterial infections are a grand challenge to global medical and health
systems. Therefore, it is urgent to develop versatile antibacterial strategies that can combat …
systems. Therefore, it is urgent to develop versatile antibacterial strategies that can combat …
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