Immunogenic Peptide Identification in H1N1 Virus as Target for Vaccine Design

N Lohia - 2017 - shodhganga.inflibnet.ac.in
Last 100 years have witnessed two pandemic outbreaks of H1N1 influenza viz. Spanish flu
in 1918 and swine flu in 2009. It has been the most prevalent subtype of influenza virus in …

Highly conserved hemagglutinin peptides of H1N1 influenza virus elicit immune response

N Lohia, M Baranwal - 3 Biotech, 2018 - Springer
In the current study, two highly conserved (> 90%) H1N1 hemagglutinin peptides
STDTVDTVLEKNVTVTHSVNL (H1) and KVNSVIEKMNTQFTAVGKEF (H2) containing …

Prediction of epitopes in hemagglutinin and neuraminidase proteins of influenza A virus H5N1 strain: a clue for diagnostic and vaccine development

P Somvanshi, V Singh, PK Seth - OMICS A Journal of Integrative …, 2008 - liebertpub.com
The avian influenza is an important infectious disease of birds. The genome of influenza A
virus was segmented, single-stranded, negative-sense RNA molecules, which encodes …

Identification of conserved peptides comprising multiple T cell epitopes of matrix 1 protein in H1N1 influenza virus

N Lohia, M Baranwal - Viral immunology, 2015 - liebertpub.com
Cell mediated immune response plays a key role in combating viral infection and thus
identification of new vaccine targets manifesting T cell mediated response may serve as an …

[PDF][PDF] IDENTIFICATION OF POTENTIAL T CELL EPITOPES OF H1N1 INFLUENZA VIRUS FOR VACCINE DESIGN-AN IMMUNOINFORMATICS AND MOLECULAR …

K AKILA, G BALAPRAKASH… - UTTAR PRADESH …, 2021 - researchgate.net
ABSTRACT H1N1 Influenza virus, otherwise known as swine flu is one of the subtypes of
influenza A virus. The H1N1 flu spreads rapidly from human to human while sneezing and …

Conserved peptides containing overlapping CD4+ and CD8+ T-cell epitopes in the H1N1 influenza virus: an immunoinformatics approach

N Lohia, M Baranwal - Viral Immunology, 2014 - liebertpub.com
Pandemic threats of the H1N1 influenza virus have drawn attention to developing a
universal vaccine against circulating and future strains of this virus. An immunoinformatics …

HLA Class I Binding 9mer Peptides from Influenza A Virus Induce CD4+ T Cell Responses

M Wang, MV Larsen, M Nielsen, M Harndahl… - PloS one, 2010 - journals.plos.org
Background Identification of human leukocyte antigen class I (HLA-I) restricted cytotoxic T
cell (CTL) epitopes from influenza virus is of importance for the development of new effective …

Immunoinformatic Prediction of the Influenza a Virus T Cell Epitope and Screening for Conserved HLA-A2-Restricted Peptides for Universal Vaccine Development

Y Tao, X Han, Y Cun, M Wang, T Lu, L Zhu, C Li… - Available at SSRN … - papers.ssrn.com
Universal influenza vaccines targeting the conserved T cell epitope may induce a T cell
response and provide long-lasting protection against multiple strains of the influenza virus …

An immunoinformatics approach in design of synthetic peptide vaccine against influenza virus

N Lohia, M Baranwal - Immunoinformatics, 2020 - Springer
Peptide-based vaccines are an appealing strategy which involves usage of short synthetic
peptides to engineer a highly targeted immune response. These short synthetic peptides …

Screening of random peptide library of hemagglutinin from pandemic 2009 A (H1N1) influenza virus reveals unexpected antigenically important regions

W Xu, L Han, Z Lin - PloS one, 2011 - journals.plos.org
The antigenic structure of the membrane protein hemagglutinin (HA) from the 2009 A
(H1N1) influenza virus was dissected with a high-throughput screening method using …