Hydrogen peroxide. Ubiquitous in cell culture and in vivo?

B Halliwell, MV Clement, J Ramalingam, LH Long - IUBMB life, 2000 - Wiley Online Library
Abstract Hydrogen peroxide (H2O2) is widely regarded as a cytotoxic agent whose levels
must be minimized by the action of antioxidant defence enzymes. In fact, H2O2 is poorly …

Hydrogen peroxide: a signaling messenger

JR Stone, S Yang - Antioxidants & redox signaling, 2006 - liebertpub.com
Hydrogen peroxide (H2O2) is a well-documented component of living cells. It plays
important roles in host defense and oxidative biosynthetic reactions. In addition there is …

[HTML][HTML] Hydrogen peroxide in the human body

B Halliwell, MV Clement, LH Long - FEBS letters, 2000 - Elsevier
Hydrogen peroxide (H2O2) is widely regarded as a cytotoxic agent whose levels must be
minimized by the action of antioxidant defence enzymes. In fact, H2O2 is poorly reactive in …

Does hydrogen peroxide exist “free” in biological systems?

J Schubert, JW Wilmer - Free Radical Biology and Medicine, 1991 - Elsevier
Abstract Hydrogen peroxide (H 2 O 2) can diffuse far from the site of production to
intracellular locations where biological effects may be greater. The diffusion range is …

Hydrogen peroxide and the proliferation of BHK-21 cells

RH Burdon, D Alliangana, V Gill - Free radical research, 1995 - Taylor & Francis
Intracellular levels of H2O2 in BHK-21 cells are not static but decline progressively with cell
growth. Exposure of cells to inhibitors of catalase, or glutathione peroxidase, not only …

What is the concentration of hydrogen peroxide in blood and plasma?

HJ Forman, A Bernardo, KJA Davies - Archives of biochemistry and …, 2016 - Elsevier
The concentration of hydrogen peroxide (H 2 O 2) in blood and plasma is a measurement
that has often been made, but the absolute values remain unsettled due the great variability …

The production of hydroxyl radical from hydrogen peroxide

TM Florence - Journal of inorganic biochemistry, 1984 - Elsevier
The formation of hydroxyl radical (OH·) from the oxidation of glutathione, ascorbic acid,
NADPH, hydroquinone, catechol, and riboflavin by hydrogen peroxide was studied using a …

[HTML][HTML] The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide

AR Giandomenico, GE Cerniglia, JE Biaglow… - Free Radical Biology …, 1997 - Elsevier
Instability of hydrogen peroxide solutions was noted during the experimental exposure of
human cells in culture to hydrogen peroxide in experiments designed to study the …

[HTML][HTML] An assay for the rate of removal of extracellular hydrogen peroxide by cells

BA Wagner, JR Witmer, TJ van't Erve, GR Buettner - Redox biology, 2013 - Elsevier
Cells have a wide range of capacities to remove extracellular hydrogen peroxide. At higher
concentrations of extracellular H 2 O 2 (micromolar) the rate of removal can be …

Hydrogen peroxide suppresses U937 cell death by two different mechanisms depending on its concentration

BR Lee, HD Um - Experimental cell research, 1999 - Elsevier
To investigate the mechanisms of H2O2adaptation in mammalian cells, we exposed human
U937 leukemia cells to 0.05 mM H2O2. This treatment significantly suppressed cell death …