Aim To examine whether the brain exhibits metabolic disorder prior to overt hepatic
encephalopathy in patients with liver cirrhosis (LC), the intracerebral glutamine and myo …

Objective To evaluate regional cerebral metabolic changes in minimal hepatic
encephalopathy (MHE) patients using magnetic resonance spectroscopy (MRS) in 3T …

Abstract BACKGROUND & AIMS: Hepatic encephalopathy (HE) is associated with typical
changes of cerebral metabolite pattern observed by proton magnetic resonance (MR) …

ABSTRACT Background/Aims: Hepatic encephalopathy is a serious problem in patients with
liver cirrhosis and precise pathophysiological mechanisms responsible for encephalopathy …

Purpose To conduct the first investigation on thalamic metabolic alterations in minimal
hepatic encephalopathy (MHE) and elucidate their association with intrinsic neural activity …

OBJECTIVE: Proton magnetic resonance spectroscopy (1 H-MRS) has been used to assess
the metabolic changes in the brain in patients with liver cirrhosis. Decreased myo-inositol …

Hepatic encephalopathy is a common problem in cirrhosis. The pathogenesis of this
complication of advanced liver disease still remains unclear. Magnetic resonance …

Background and study aim Minimal hepatic encephalopathy (MHE) is a subtle complication
of cirrhosis that may have a detrimental effect on daily functioning and may progress to overt …

Brain magnetic resonance (MR) study has shown metabolic abnormalities and changes in
water distribution of the brain tissue that may relate to the pathogenesis of hepatic …

Results The brain metabolite Glx increased with a significant correlation to HE grade (p=
0.001). Other brain metabolites, such as Cho and mI, decreased significantly (p= 0.001) …