Mechanistic pathways of malignancy in breast cancer stem cells

S Yousefnia, F Seyed Forootan… - Frontiers in …, 2020 - frontiersin.org
Breast cancer stem cells (BCSCs) are the minor population of breast cancer (BC) cells that
exhibit several phenotypes such as migration, invasion, self-renewal, and chemotherapy as …

[HTML][HTML] Role, molecular mechanism and the potential target of breast cancer stem cells in breast cancer development

T Zhang, H Zhou, K Wang, X Wang, M Wang… - Biomedicine & …, 2022 - Elsevier
Breast cancer (BC) is one of the most common malignant tumors in women globally, and its
occurrence has surpassed lung cancer and become the biggest threat for women. At …

Signaling pathways governing breast cancer stem cells behavior

K Song, M Farzaneh - Stem Cell Research & Therapy, 2021 - Springer
Breast cancer is the second common cancer and the leading cause of malignancy among
females overall. Breast cancer stem cells (BCSCs) are a small population of breast cancer …

Signaling pathways governing the maintenance of breast cancer stem cells and their therapeutic implications

A Ordaz-Ramos, O Tellez-Jimenez… - Frontiers in cell and …, 2023 - frontiersin.org
Breast cancer stem cells (BCSCs) represent a distinct subpopulation of cells with the ability
to self-renewal and differentiate into phenotypically diverse tumor cells. The involvement of …

Targeting cellular signaling pathways in breast cancer stem cells and its implication for cancer treatment

BRB Pires, ÍSS DE AMORIM, LDE Souza… - Anticancer …, 2016 - ar.iiarjournals.org
Breast cancer is a public health problem both in developing and developed countries. The
breast cancer stem cell (BCSC) hypothesis has grown in the cancer research community …

Breast cancer stem cells

JS Crabtree, L Miele - Biomedicines, 2018 - mdpi.com
Breast cancer stem cells (BCSC) have been implicated in tumor initiation, progression,
metastasis, recurrence, and resistance to therapy. The origins of BCSCs remain …

MicroRNAs, a promising target for breast cancer stem cells

PK Das, MA Siddika, SY Asha, S Aktar… - Molecular Diagnosis & …, 2020 - Springer
Reactivation of the stem cell programme in breast cancer is significantly associated with
persistent cancer progression and therapeutic failure. Breast cancer stem cells (BCSCs) are …

Breast cancer stem cells: Signaling pathways, cellular interactions, and therapeutic implications

L Wang, Z Jin, RP Master, CK Maharjan, ME Carelock… - Cancers, 2022 - mdpi.com
Simple Summary Cancer stem cells (CSCs) in breast cancer have been identified for almost
two decades. Many outstanding discoveries have established the important functions of …

MicroRNA regulation of human breast cancer stem cells

Y Shimono, J Mukohyama, S Nakamura… - Journal of clinical …, 2015 - mdpi.com
MicroRNAs (miRNAs) are involved in virtually all biological processes, including stem cell
maintenance, differentiation, and development. The dysregulation of miRNAs is associated …

Heterogeneity of tumors in breast cancer: implications and prospects for prognosis and therapeutics

N Tuasha, B Petros - Scientifica, 2020 - Wiley Online Library
Breast cancer is the most commonly diagnosed form of cancer in women comprising 16% of
all female cancers. The disease shows high intertumoral and intratumoral heterogeneity …