In the past decade, the inner nuclear membrane has become a focus of research on
inherited diseases. A heterogeneous group of genetic disorders known as laminopathies …

Mutations in nuclear lamins A and C, intermediate filament proteins of the nuclear envelope,
cause diseases affecting various tissues and the aging process. We review what is known …

The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear
pore complexes. In recent years, mutations in nuclear‐envelope proteins have been shown …

Nuclear lamins are intermediate filament proteins that polymerize to form the nuclear lamina
on the inner aspect of the inner nuclear membrane. Long known to be essential for …

Nuclear lamins form a fibrous nucleoskeletal network of intermediate‐sized filaments that
underlies the inner nuclear membrane. It associates with this membrane through …

The nuclear lamina is a filamentous structure composed of lamins that supports the inner
nuclear membrane. Several integral membrane proteins including emerin, LBR, LAP1 and …

The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear
pore complexes. Laminopathies are diseases caused by mutations in genes encoding …

Just at the beginning of the millennium the neologism laminopathies has been introduced in
the scientific vocabulary. An exponential increase of interest on the subject started …

Lamin proteins are the major constituents of the nuclear lamina, a proteinaceous network
that lines the inner nuclear membrane. Primarily, the nuclear lamina provides structural …

Mutations in genes encoding nuclear lamins and associated nuclear envelope proteins
have been linked to a broad range of inherited diseases affecting different tissues and …