Eight key rules for successful data‐dependent acquisition in mass spectrometry‐based metabolomics

E Defossez, J Bourquin, S von Reuss… - Mass Spectrometry …, 2023 - Wiley Online Library
In recent years, metabolomics has emerged as a pivotal approach for the holistic analysis of
metabolites in biological systems. The rapid progress in analytical equipment, coupled to the …

Current challenges and recent developments in mass spectrometry–based metabolomics

SL Collins, I Koo, JM Peters, PB Smith… - Annual review of …, 2021 - annualreviews.org
High-resolution mass spectrometry (MS) has advanced the study of metabolism in living
systems by allowing many metabolites to be measured in a single experiment. Although …

[HTML][HTML] Mass appeal: metabolite identification in mass spectrometry-focused untargeted metabolomics

WB Dunn, A Erban, RJM Weber, DJ Creek, M Brown… - Metabolomics, 2013 - Springer
Metabolomics has advanced significantly in the past 10 years with important developments
related to hardware, software and methodologies and an increasing complexity of …

Data processing for mass spectrometry-based metabolomics

M Katajamaa, M Orešič - Journal of chromatography A, 2007 - Elsevier
Modern analytical technologies afford comprehensive and quantitative investigation of a
multitude of different metabolites. Typical metabolomic experiments can therefore produce …

Data acquisition workflows in liquid chromatography coupled to high resolution mass spectrometry-based metabolomics: Where do we stand?

F Fenaille, PB Saint-Hilaire, K Rousseau… - … of Chromatography a, 2017 - Elsevier
Typical mass spectrometry (MS) based untargeted metabolomics protocols are tedious as
well as time-and sample-consuming. In particular, they often rely on “full-scan-only” …

Untargeted metabolomics strategies—challenges and emerging directions

AC Schrimpe-Rutledge, SG Codreanu… - Journal of the …, 2016 - ACS Publications
Metabolites are building blocks of cellular function. These species are involved in enzyme-
catalyzed chemical reactions and are essential for cellular function. Upstream biological …

Technical challenges in mass spectrometry-based metabolomics

F Matsuda - Mass spectrometry, 2016 - jstage.jst.go.jp
Metabolomics is a strategy for analysis, and quantification of the complete collection of
metabolites present in biological samples. Metabolomics is an emerging area of scientific …

[HTML][HTML] Advancing untargeted metabolomics using data-independent acquisition mass spectrometry technology

R Wang, Y Yin, ZJ Zhu - Analytical and Bioanalytical Chemistry, 2019 - Springer
Metabolomics quantitatively measures metabolites in a given biological system and
facilitates the understanding of physiological and pathological activities. With the recent …

Overview of mass spectrometry-based metabolomics: opportunities and challenges

GAN Gowda, D Djukovic - Mass Spectrometry in Metabolomics: Methods …, 2014 - Springer
The field of metabolomics has witnessed an exponential growth in the last decade driven by
important applications spanning a wide range of areas in the basic and life sciences and …

Current state of the art of mass spectrometry-based metabolomics studies–a review focusing on wide coverage, high throughput and easy identification

Y Wang, S Liu, Y Hu, P Li, JB Wan - Rsc Advances, 2015 - pubs.rsc.org
Metabolomics aims at the comprehensive assessment of a wide range of endogenous
metabolites and attempts to identify and quantify the attractive metabolites in a given …