Metabolism is the collection of biochemical reactions enabled by chemically diverse
metabolites, which facilitate different physiological processes to exchange substances and …

This Feature Article highlights some of the key challenges within the field of metabolomics
and examines what role separation and analytical sciences can play to improve the use of …

Untargeted metabolomics aims to quantify the complete set of metabolites within a biological
system, most commonly by liquid chromatography/mass spectrometry (LC/MS). Since nearly …

The computational metabolomics field brings together computer scientists, bioinformaticians,
chemists, clinicians, and biologists to maximize the impact of metabolomics across a wide …

Rapid advances in mass spectrometry (MS) and nuclear magnetic resonance (NMR)‐based
platforms for metabolomics have led to an upsurge of data every single year. Newer high …

In untargeted metabolomics, conventional data preprocessing software (eg, XCMS, MZmine
2, MS-DIAL) are used extensively due to their high efficiency in metabolic feature extraction …

Metabolomics offers a revolutionary framework for phenotyping individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …

Background: Metabolomics is increasingly recognized as an invaluable tool in the
biological, medical and environmental sciences yet lags behind the methodological maturity …

The scale at which MS‐and NMR‐based platforms generate metabolomics datasets for both
research, core, and clinical facilities to address challenges in the various sciences—ranging …

Metabolomics analysis generates vast arrays of data, necessitating comprehensive
workflows involving expertise in analytics, biochemistry and bioinformatics in order to …