In patients with COPD, an acute worsening of respiratory symptoms is often described as an
exacerbation. Exacerbations are associated with a significant increase in mortality …

Efforts to assess the efficacy of new therapies in the treatment of acute exacerbations of
chronic obstructive pulmonary disease (COPD) have been hampered by the lack of a widely …

Chronic obstructive pulmonary disease (COPD) is defined independently of exacerbations,
which are largely a feature of moderate-to-severe disease. This article is the result of a …

Organisation/US National Heart Lung and Blood Institute global initiative for chronic
obstructive lung disease (GOLD) guideline was made available online. 1 We applaud those …

Chronic obstructive pulmonary disease (COPD) is associated with episodes of acute
deterioration in respiratory health termed “exacerbations.” Exacerbations are characterized …

Chronic obstructive pulmonary disease (COPD) is a chronic illness that can be periodically
punctuated by exacerbations, characterised by acute worsening of symptoms, including …

Over 200 years ago, René Laennec published the first description of emphysema, an
important pathobiological element of what is today known as chronic obstructive pulmonary …

Chronic obstructive pulmonary disease (COPD) is a progressive disorder of airflow limitation
that is not fully reversible, with disabling symptoms including chronic cough and dyspnoea …

Background: Frequent exacerbations are associated with a faster decline in FEV 1, impaired
health status, and worse survival. Their impact and temporal relationship with other …

Clinical trials evaluating the management of acute exacerbations of COPD assess
heterogeneous outcomes, often omitting those that are clinically relevant or more important …