Chromatin remodeling in neural development and plasticity
Neural stem cells generate distinct cell types for tissue formation and cell replacement
during development and throughout adulthood. Neural development and plasticity are …
during development and throughout adulthood. Neural development and plasticity are …
Chromatin regulation of neuronal maturation and plasticity
DA Gallegos, U Chan, LF Chen, AE West - Trends in neurosciences, 2018 - cell.com
Neurons are dynamic cells that respond and adapt to stimuli throughout their long
postmitotic lives. The structural and functional plasticity of neurons requires the regulated …
postmitotic lives. The structural and functional plasticity of neurons requires the regulated …
[HTML][HTML] Decoding the epigenetic language of neuronal plasticity
Neurons are submitted to an exceptional variety of stimuli and are able to convert these into
high-order functions, such as storing memories, controlling behavior, and governing …
high-order functions, such as storing memories, controlling behavior, and governing …
[HTML][HTML] Histone regulation in the CNS: basic principles of epigenetic plasticity
I Maze, KM Noh, CD Allis - Neuropsychopharmacology, 2013 - nature.com
Postmitotic neurons are subject to a vast array of environmental influences that require the
nuclear integration of intracellular signaling events to promote a wide variety of neuroplastic …
nuclear integration of intracellular signaling events to promote a wide variety of neuroplastic …
[HTML][HTML] The role of histone modifications: from neurodevelopment to neurodiseases
J Park, K Lee, K Kim, SJ Yi - Signal transduction and targeted therapy, 2022 - nature.com
Epigenetic regulatory mechanisms, including DNA methylation, histone modification,
chromatin remodeling, and microRNA expression, play critical roles in cell differentiation …
chromatin remodeling, and microRNA expression, play critical roles in cell differentiation …
[HTML][HTML] Critical role of histone turnover in neuronal transcription and plasticity
Turnover and exchange of nucleosomal histones and their variants, a process long believed
to be static in post-replicative cells, remains largely unexplored in brain. Here, we describe a …
to be static in post-replicative cells, remains largely unexplored in brain. Here, we describe a …
Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways
A Riccio - Nature neuroscience, 2010 - nature.com
The development and function of neurons require the regulated expression of large
numbers of very specific gene sets. Epigenetic modifications of both DNA and histone …
numbers of very specific gene sets. Epigenetic modifications of both DNA and histone …
Epigenetic control of neural stem cell fate
Unraveling the mechanisms by which neural stem cells generate distinct cell types remains
a central challenge in central nervous system (CNS) biology. Recent studies have shown …
a central challenge in central nervous system (CNS) biology. Recent studies have shown …
[HTML][HTML] The emerging role of chromatin remodelers in neurodevelopmental disorders: a developmental perspective
B Mossink, M Negwer, D Schubert… - Cellular and Molecular …, 2021 - Springer
Neurodevelopmental disorders (NDDs), including intellectual disability (ID) and autism
spectrum disorders (ASD), are a large group of disorders in which early insults during brain …
spectrum disorders (ASD), are a large group of disorders in which early insults during brain …
Epigenetic mechanisms: critical contributors to long-term memory formation
Recent advances in chromatin biology have identified a role for epigenetic mechanisms in
the regulation of neuronal gene expression changes, a necessary process for proper …
the regulation of neuronal gene expression changes, a necessary process for proper …