Control and dysregulation of redox signalling in the gastrointestinal tract
EL Campbell, SP Colgan - Nature Reviews Gastroenterology & …, 2019 - nature.com
Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …
Redox biology of the intestine
ML Circu, TY Aw - Free radical research, 2011 - Taylor & Francis
The intestinal tract, known for its capability for self-renew, represents the first barrier of
defence between the organism and its luminal environment. The thiol/disulfide redox …
defence between the organism and its luminal environment. The thiol/disulfide redox …
Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets
F Biasi, G Leonarduzzi, PI Oteiza… - Antioxidants & redox …, 2013 - liebertpub.com
Oxidative stress is thought to play a key role in the development of intestinal damage in
inflammatory bowel disease (IBD), because of its primary involvement in intestinal cells' …
inflammatory bowel disease (IBD), because of its primary involvement in intestinal cells' …
Redox signaling mediated by the gut microbiota
AS Neish - Free radical research, 2013 - Taylor & Francis
The microbiota that occupies the mammalian intestine can modulate a range of
physiological functions, including control over immune responses, epithelial barrier function …
physiological functions, including control over immune responses, epithelial barrier function …
ROS in gastrointestinal inflammation: rescue or sabotage?
The intestine is composed of many distinct cell types that respond to commensal microbiota
or pathogens with immune tolerance and proinflammatory signals respectively. ROS …
or pathogens with immune tolerance and proinflammatory signals respectively. ROS …
Redox signaling in the gastrointestinal tract
S Pérez, R Taléns-Visconti, S Rius-Pérez… - Free Radical Biology …, 2017 - Elsevier
Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …
Redox signaling mediated by the gut microbiota
The microbiota that inhabits the mammalian intestine can influence a range of physiological
functions, including the modulation of immune responses, enhancement epithelial barrier …
functions, including the modulation of immune responses, enhancement epithelial barrier …
The influence of gut microbiota on oxidative stress and the immune system
C Kunst, S Schmid, M Michalski, D Tümen… - Biomedicines, 2023 - mdpi.com
The human gastrointestinal tract is home to a complex microbial community that plays an
important role in the general well-being of the entire organism. The gut microbiota generates …
important role in the general well-being of the entire organism. The gut microbiota generates …
Intestinal redox biology and oxidative stress
ML Circu, TY Aw - Seminars in cell & developmental biology, 2012 - Elsevier
The intestinal epithelium sits at the interface between an organism and its luminal
environment, and as such is prone to oxidative damage induced by luminal oxidants …
environment, and as such is prone to oxidative damage induced by luminal oxidants …
Role of oxygen gradients in shaping redox relationships between the human intestine and its microbiota
MG Espey - Free Radical Biology and Medicine, 2013 - Elsevier
The unique anatomy and physiology of the intestine in conjunction with its microbial content
create the steepest oxygen gradients in the body, which plunge to near anoxia at the luminal …
create the steepest oxygen gradients in the body, which plunge to near anoxia at the luminal …