Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …

The intestinal tract, known for its capability for self-renew, represents the first barrier of
defence between the organism and its luminal environment. The thiol/disulfide redox …

Oxidative stress is thought to play a key role in the development of intestinal damage in
inflammatory bowel disease (IBD), because of its primary involvement in intestinal cells' …

The microbiota that occupies the mammalian intestine can modulate a range of
physiological functions, including control over immune responses, epithelial barrier function …

The intestine is composed of many distinct cell types that respond to commensal microbiota
or pathogens with immune tolerance and proinflammatory signals respectively. ROS …

Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

The microbiota that inhabits the mammalian intestine can influence a range of physiological
functions, including the modulation of immune responses, enhancement epithelial barrier …

The human gastrointestinal tract is home to a complex microbial community that plays an
important role in the general well-being of the entire organism. The gut microbiota generates …

The intestinal epithelium sits at the interface between an organism and its luminal
environment, and as such is prone to oxidative damage induced by luminal oxidants …

The unique anatomy and physiology of the intestine in conjunction with its microbial content
create the steepest oxygen gradients in the body, which plunge to near anoxia at the luminal …