High impulsivity predicts relapse to cocaine-seeking after punishment-induced abstinence
BACKGROUND: Relapse is a hallmark feature of cocaine addiction and a main challenge
for treatment strategies. Human studies indicate a link between impulsivity and increased …
for treatment strategies. Human studies indicate a link between impulsivity and increased …
Trait impulsive choice predicts resistance to extinction and propensity to relapse to cocaine seeking: a bidirectional investigation
N Broos, L Diergaarde, ANM Schoffelmeer… - …, 2012 - nature.com
Despite the strong association between impulsivity and addiction in humans, it is still a
matter of debate whether impulsive choice predisposes to, or results from, drug …
matter of debate whether impulsive choice predisposes to, or results from, drug …
Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking
D Economidou, JW Dalley, BJ Everitt - Biological psychiatry, 2011 - Elsevier
BACKGROUND:: Preventing relapse to drug use is a major challenge for drug addiction
treatment. We have recently shown that impulsivity predating drug-taking increases the …
treatment. We have recently shown that impulsivity predating drug-taking increases the …
Unidirectional relationship between heroin self-administration and impulsive decision-making in rats
MC Schippers, R Binnekade, ANM Schoffelmeer… - …, 2012 - Springer
Rationale There is growing clinical evidence for a strong relationship between drug
addiction and impulsivity. However, it is not fully clear whether impulsivity is a pre-existing …
addiction and impulsivity. However, it is not fully clear whether impulsivity is a pre-existing …
Impulsivity predicts the escalation of cocaine self-administration in rats
JJ Anker, JL Perry, LA Gliddon, ME Carroll - … Biochemistry and Behavior, 2009 - Elsevier
Impulsivity, as measured by the delay-discounting task, predicts the acquisition of cocaine
self-administration and reinstatement of cocaine seeking in rats. The purpose of this study …
self-administration and reinstatement of cocaine seeking in rats. The purpose of this study …
The role of impulsive behavior in drug abuse
JL Perry, ME Carroll - Psychopharmacology, 2008 - Springer
Background Impulsivity is a multifaceted construct that has recently been recognized as a
factor contributing to enhanced vulnerability to drug abuse. Objectives In the present review …
factor contributing to enhanced vulnerability to drug abuse. Objectives In the present review …
The role of impulsivity in relapse vulnerability
T Pattij, TJ De Vries - Current opinion in neurobiology, 2013 - Elsevier
Drug dependence in humans is often accompanied by behavioral disturbances such as
maladaptive levels of impulsivity. In turn, there is accumulating evidence from preclinical …
maladaptive levels of impulsivity. In turn, there is accumulating evidence from preclinical …
Trait-like impulsivity does not predict escalation of heroin self-administration in the rat
Rationale The neural and psychological mechanisms underlying vulnerability to drug
addiction are poorly understood. Although a number of animal models have been …
addiction are poorly understood. Although a number of animal models have been …
Effects of chronic cocaine on impulsivity: relation to cortical serotonin mechanisms
TA Paine, HC Dringenberg, MC Olmstead - Behavioural Brain Research, 2003 - Elsevier
Drug addiction can be considered an impulse control disorder in that addicts exhibit
increased impulsivity on both behavioural and self-report measures. We investigated …
increased impulsivity on both behavioural and self-report measures. We investigated …
The relationship between impulsivity and craving in cocaine-and methamphetamine-dependent volunteers
D Tziortzis, JJ Mahoney III, AD Kalechstein… - Pharmacology …, 2011 - Elsevier
Impulsivity and craving have been independently hypothesized to contribute to sustained
drug use and relapse in addiction. The primary focus of this project was to determine the …
drug use and relapse in addiction. The primary focus of this project was to determine the …