Microglia are the brain's resident immune cells, performing surveillance to promote
homeostasis and healthy functioning. While microglial chemical signaling is well-studied …

Microglial cells are the key immunocompetent cells in the central nervous system (CNS) and
play a crucial role in CNS health and disease (Paolicelli et al., 2022). Under the homeostatic …

Microglial cells are crucial in maintaining central nervous system (CNS) homeostasis and
mediating CNS disease pathogenesis. Increasing evidence supports that alterations in the …

Microglia are the resident macrophages of the central nervous system (CNS) that control
brain development, maintain neural environments, respond to injuries, and regulate …

Piezo1 mechanosensitive ion channel (MSC) plays a significant role in human physiology.
Despite several research on the function and expression of Piezo1 in the nervous system, its …

Background Microglia are the endogenous immune cells of the brain and act as sensors of
pathology to maintain brain homeostasis and eliminate potential threats. In Alzheimer's …

Astrocytes are important for information processing in the brain and they achieve this by fine‐
tuning neuronal communication via continuous uptake and release of biochemical …

A defining pathophysiological hallmark of Alzheimer's disease (AD) is the amyloid plaque;
an extracellular deposit of aggregated fibrillar Aβ1-42 peptides. Amyloid plaques are hard …

Macrophages are the most important innate immune cells in humans. They are almost
ubiquitous in peripheral tissues with a large variety of different mechanical milieus …

Mechanical damage is one of the predisposing factors of inflammation, and it runs through
the entire inflammatory pathological process. Repeated or persistent damaging mechanical …