Humanistic outcomes in treatment resistant depression: a secondary analysis of the STAR* D study

A DiBernardo, X Lin, Q Zhang, J Xiang, L Lu… - BMC psychiatry, 2018 - Springer
Abstract Background In the Sequenced Treatment Alternatives to Relieve Depression
(STAR* D) study, a third of patients did not achieve remission or adequate response after …

The aims and design of the Sequenced Treatment Alternatives to Relieve Depression (STAR* D) study

BN Gaynes, L Davis, AJ Rush… - Primary …, 2005 - utsouthwestern.elsevierpure.com
Major depressive disorder is expected to become the second leading cause of disability
worldwide by the year 2020. A large proportion of this disability can be attributed to the large …

What are the implications of the STAR* D trial for primary care? A review and synthesis

NN Huynh, RS McIntyre - Primary care companion to the Journal of …, 2008 - psychiatrist.com
Background: Although results of the Sequenced Treatment Alternatives to Relieve
Depression (STAR* D) trial have been widely disseminated to mental health care providers …

[HTML][HTML] Real-world evidence from a European cohort study of patients with treatment resistant depression: baseline patient characteristics

K Heerlein, AH Young, C Otte, T Frodl… - Journal of Affective …, 2021 - Elsevier
Background Treatment resistant depression (TRD; failure to respond to≥ 2 treatments)
affects~ 20% of patients with major depressive disorder (MDD). Real-world data could help …

Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR* D report

AJ Rush, MH Trivedi, SR Wisniewski… - American Journal of …, 2006 - Am Psychiatric Assoc
Objective: This report describes the participants and compares the acute and longer-term
treatment outcomes associated with each of four successive steps in the Sequenced …

Current perspectives in the management of treatment-resistant depression

RM Parikh, BD Lebowitz - Dialogues in Clinical Neuroscience, 2004 - Taylor & Francis
Depressive disorders are a leading cause of disability worldwide and greatly impact
morbidity, health care utilization, and medical costs. Major depression that does not resolve …

Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR* D report

AJ Rush, MH Trivedi, SR Wisniewski, AA Nierenberg… - Focus, 2008 - Am Psychiatric Assoc
Objective: This report describes the participants and compares the acute and longer-term
treatment outcomes associated with each of four successive steps in the Sequenced …

The humanistic and economic burden of treatment-resistant depression in Europe: a cross-sectional study

DH Jaffe, B Rive, TR Denee - BMC psychiatry, 2019 - Springer
Background A patient is considered to suffer from treatment resistant depression (TRD)
when consecutive treatment with two products of different pharmacological classes, used for …

The STAR* D study: treating depression in the real world.

BN Gaynes, AJ Rush, MH Trivedi… - … Clinic journal of …, 2008 - europepmc.org
The Sequenced Treatment Alternatives to Relieve Depression (STAR* D) study evaluated
feasible treatment strategies to improve clinical outcomes for real-world patients with …

What are the treatment remission, response and extent of improvement rates after up to four trials of antidepressant therapies in real-world depressed patients? A …

HE Pigott, T Kim, C Xu, I Kirsch, J Amsterdam - BMJ open, 2023 - bmjopen.bmj.com
Objective Reanalyse the patient-level data set of the Sequenced Treatment Alternatives to
Relieve Depression (STAR* D) study with fidelity to the original research protocol and …