Importance Advances in childhood and adolescent cancer treatment have been associated
with increased rates of cure during the past 3 decades; however, improvement in adult life …

PURPOSE: Survivors of childhood and adolescent cancer are at risk for long-term effects of
disease and treatment. The Childhood Cancer Survivor Study assessed overall and cause …

The Childhood Cancer Survivor Study (CCSS) has assembled the largest cohort to date for
assessment of late mortality. Vital status and cause of death of all patients eligible for …

Background Among patients in whom childhood cancer was diagnosed in the 1970s and
1980s, 18% of those who survived for 5 years died within the subsequent 25 years. In recent …

Background The proportion of pediatric and adolescent cancer patients surviving 5 years
has increased during the past four decades. This growing population of survivors remains at …

Survivors of childhood and adolescent cancer are at risk for long‐term effects of disease and
treatment. The Childhood Cancer Survivor Study assessed overall and cause‐specific …

PURPOSE To determine the frequency and patterns of late mortality among long-term
survivors of childhood cancer. MATERIALS AND METHODS Medical records of patients who …

Background: Although childhood cancer survival rates have dramatically increased,
survivors face elevated risk for life-threatening late effects, including secondary cancer …

The successful treatment of pediatric malignancy by multimodality therapy has improved the
outcome for children with cancer. It has been estimated that 0.1% of individuals 20 years of …

During the past 30 years, changes in the treatment of children and adolescents with cancer
have led to substantial improvements in survival. Although treatment‐related factors have …