The basal forebrain cholinergic system has been implicated in the reorganization of adult
cortical sensory and motor representations under many, but not all, experimental conditions …

It has not been possible to analyze the cellular mechanisms underlying learning in behaving
mammals because of the difficulties in recording intracellularly from awake animals …

We developed a model of 545 components (nodes) and 1259 interactions representing
signaling pathways and cellular machines in the hippocampal CA1 neuron. Using graph …

Receptive field (RF) plasticity develops in the primary auditory cortex (ACx) when a tone
conditioned stimulus (CS) becomes associated with an appetitive or aversive unconditioned …

We learn complex skills such as speech and dance through a gradual process of trial and
error. Cortical-basal ganglia circuits have an important yet unresolved function in this trial …

The hippocampus computes diverse information involving spatial memory, anxiety, or
reward and directly projects to several brain areas. Are different computations transmitted to …

It is controversial whether the adult primate early visual cortex is sufficiently plastic to cause
visual perceptual learning (VPL). The controversy occurs partially because most VPL studies …

The central auditory system translates sound localization cues into a map of space guided,
in part, by visual experience. In barn owls, this process takes place in the external nucleus of …

The nucleus basalis (NB) has been implicated in memory formation indirectly, by lesions,
pharmacological manipulations, and neural correlates of learning. Prior findings imply that …

INTRODUCTION Tool use is a hallmark of human evolution. Beyond its sensorimotor
components, the complexity of which has been extensively investigated, tool use affects …