Following restricted peripheral damage, reorganization of adult sensory or motor cortex is
believed to depend on loss of surround inhibition, which unmasks latent inputs to the …

Experience-dependent changes in behavior are mediated by long-term functional
modifications in brain circuits. Activity-dependent plasticity of synaptic input is a major …

The organization of the hippocampus is generally thought of as a series of cell groups that
form a unidirectionally excited chain, regulated by localized inhibitory circuits. With the use …

The possibility that neurons in the basal ganglia and cerebellum innervate areas of the
cerebral cortex that are involved in cognitive function has been a controversial subject. Here …

The primate basal ganglia receives information from most of the cerebrum, including the
frontal cortex, but projects (via the dorsal thalamus) primarily to the frontal lobe, perhaps in …

It is well known that early disruption of sensory input from one modality can induce
crossmodal reorganization of a deprived cortical area, resulting in compensatory abilities in …

Cortical sensory processing is modulated by behavioral and cognitive states. How this
modulation is achieved by changing synaptic circuits remains largely unknown. In awake …

In vivo intracellular recordings of hippocampal neurons reveal the occurrence of fast events
of small amplitude called spikelets or fast prepotentials. Because intracellular recordings …

Do new synapses form in the adult cortex to support experience-dependent plasticity? To
address this question, we repeatedly imaged individual pyramidal neurons in the mouse …

The development of cortical layers, areas and networks is mediated by a combination of
factors that are present in the cortex and are influenced by thalamic input. Electrical activity …