Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels
N Gilhotra, D Dhingra - Pharmacological Reports, 2011 - Springer
The aim of the present study was to investigate the role of GABAergic and nitriergic
modulation in the antianxiety effect of thymoquinone, a major constituent of Nigella sativa, in …
modulation in the antianxiety effect of thymoquinone, a major constituent of Nigella sativa, in …
Antianxiety-like activity of gallic acid in unstressed and stressed mice: possible involvement of nitriergic system
D Dhingra, R Chhillar, A Gupta - Neurochemical Research, 2012 - Springer
The aim of present study was to evaluate antianxiety-like activity of gallic acid in Swiss
young male albino mice; and to explore the possible underlying mechanisms for this activity …
young male albino mice; and to explore the possible underlying mechanisms for this activity …
Involvement of NO–cGMP pathway in anti-anxiety effect of aminoguanidine in stressed mice
N Gilhotra, D Dhingra - Progress in Neuro-Psychopharmacology and …, 2009 - Elsevier
In the present study, effect of aminoguanidine (12.5, 25 and 50mg/kg, ip), a selective
inhibitor of inducible nitric oxide synthase, was evaluated for its anti-anxiety activity in …
inhibitor of inducible nitric oxide synthase, was evaluated for its anti-anxiety activity in …
GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice
N Gilhotra, D Dhingra - Brain research, 2010 - Elsevier
In the present study, effect of curcumin (10 and 20mg/kg), an active constituent of Curcuma
longa was evaluated for its antianxiety-like activity in mice subjected to immobilization …
longa was evaluated for its antianxiety-like activity in mice subjected to immobilization …
The effects of Nigella sativa hydro-alcoholic extract and thymoquinone on lipopolysaccharide-induced depression like behavior in rats
M Hosseini, S Zakeri, S Khoshdast… - Journal of Pharmacy …, 2012 - journals.lww.com
Background: Neuroimmune factors have been proposed as contributors to the pathogenesis
of depression. Beside other therapeutic effects including neuroprotective, antioxidant …
of depression. Beside other therapeutic effects including neuroprotective, antioxidant …
Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice
Depression is an inflammatory, commonly occurring and lethal psychiatric disorder having
high lifetime prevalence. Preclinical and clinical studies suggest that activation of immuno …
high lifetime prevalence. Preclinical and clinical studies suggest that activation of immuno …
Therapeutic effect of Thymoquinone on behavioural response to UCMS and neuroinflammation in hippocampus and amygdala in BALB/c mice model
Rationale Major depressive disorder is the leading cause of disability worldwide. The
corticolimbic system plays a critical role in the emotional and cognitive aspects of major …
corticolimbic system plays a critical role in the emotional and cognitive aspects of major …
Beneficial effect of honokiol on lipopolysaccharide induced anxiety-like behavior and liver damage in mice
Anxiety disorders are commonly occurring co-morbid neuropsychiatric disorders with
chronic inflammatory conditions such as live damage. Numerous studies revealed that …
chronic inflammatory conditions such as live damage. Numerous studies revealed that …
Memory enhancing activity of naringin in unstressed and stressed mice: possible cholinergic and nitriergic modulation
SR Maratha, N Mahadevan - Neurochemical research, 2012 - Springer
The present study was designed to evaluate the effect of Naringin on memory of unstressed
and stressed Swiss young albino mice. Naringin (80 mg/kg, ip) and donepezil (10 mg/kg) …
and stressed Swiss young albino mice. Naringin (80 mg/kg, ip) and donepezil (10 mg/kg) …
[HTML][HTML] Possible neuroprotective mechanisms of action involved in the neurobehavioral property of naringin in mice
B Ben-Azu, EE Nwoke, AO Aderibigbe… - Biomedicine & …, 2019 - Elsevier
Flavonoids are naturally occurring bioactive phytochemical metabolites widely known to
prevent and suppress several human diseases, and are important sources of therapeutic …
prevent and suppress several human diseases, and are important sources of therapeutic …