Host age modulates parasite infectivity, virulence and reproduction

R Izhar, F Ben‐Ami - Journal of Animal Ecology, 2015 - Wiley Online Library
Host age is one of the most striking differences among hosts within most populations, but
there is very little data on how age‐dependent effects impact ecological and evolutionary …

A computer model of the evolution of specific maximum lifespan

AR Miller - Mechanisms of Ageing and Development, 1981 - Elsevier
To answer the question of why organisms have evolved finite and specific maximum
lifespans, I have built and experimentally studied a discrete-event simulation model of the …

Health trajectories reveal the dynamic contributions of host genetic resistance and tolerance to infection outcome

G Lough, I Kyriazakis, S Bergmann… - … of the Royal …, 2015 - royalsocietypublishing.org
Resistance and tolerance are two alternative strategies hosts can adopt to survive infections.
Both strategies may be genetically controlled. To date, the relative contribution of resistance …

Evolution and emergence of novel human infections

N Arinaminpathy, AR McLean - Proceedings of the …, 2009 - royalsocietypublishing.org
Some zoonotic pathogens cause sporadic infection in humans but rarely propagate further,
while others have succeeded in overcoming the species barrier and becoming established …

Seasonality in multi-host disease systems

D Nguyen, T Wakhare, J Jiao, K Myers, O Udiani… - Ecological …, 2022 - Elsevier
Demographic processes have long been known to critically impact population-level
epidemic dynamics. Within a single ecosystem, a novel pathogen may circulate among …

Host phenology regulates parasite–host demographic cycles and eco‐evolutionary feedbacks

H MacDonald, D Brisson - Ecology and Evolution, 2022 - Wiley Online Library
Parasite–host interactions can drive periodic population dynamics when parasites
overexploit host populations. The timing of host seasonal activity, or host phenology …

Back to the future in a petri dish: Origin and impact of resurrected microbes in natural populations

S Houwenhuyse, E Macke, L Reyserhove… - Evolutionary …, 2018 - Wiley Online Library
Current natural populations face new interactions because of the re‐emergence of ancient
microbes and viruses. These risks come from the re‐emergence of pathogens kept in …

Evolutionary perspectives on health and medicine

SC Stearns, RM Nesse… - Proceedings of the …, 2010 - National Acad Sciences
pathogens, and argues forcefully that we especially need evolutionary insights when
dealing with infectious disease surveillance, gene-by-environment interactions, and global …

Parasite‐mediated selection on host phenology

H MacDonald, D Brisson - Ecology and Evolution, 2023 - Wiley Online Library
The timing of seasonal activity, or phenology, is an adaptive trait that maximizes individual
fitness by timing key life events to coincide with favorable abiotic factors and biotic …

Acquired immunity and stochasticity in epidemic intervals impede the evolution of host disease resistance

KC Harding, BJ L. Hansen… - The American …, 2005 - journals.uchicago.edu
Disease can generate intense selection pressure on host populations, but here we show
that acquired immunity in a population subject to repeated disease outbreaks can impede …