Effects of intranasal administration of oxytocin and vasopressin on social cognition and potential routes and mechanisms of action

S Yao, KM Kendrick - Pharmaceutics, 2022 - mdpi.com
Acute and chronic administration of intranasal oxytocin and vasopressin have been
extensively utilized in both animal models and human preclinical and clinical studies over …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Intranasal oxytocin effects on social cognition: a critique

SL Evans, O Dal Monte, P Noble, BB Averbeck - Brain research, 2014 - Elsevier
The last decade has seen a large number of published findings supporting the hypothesis
that intranasally delivered oxytocin (OT) can enhance the processing of social stimuli and …

Null results of oxytocin and vasopressin administration across a range of social cognitive and behavioral paradigms: Evidence from a randomized controlled trial

BA Tabak, AR Teed, E Castle, JM Dutcher… - …, 2019 - Elsevier
Research examining oxytocin and vasopressin in humans has the potential to elucidate
neurobiological mechanisms underlying human sociality that have been previously …

Sniffing oxytocin: Nose to brain or nose to blood?

S Yao, Y Chen, Q Zhuang, Y Zhang, C Lan, S Zhu… - Molecular …, 2023 - nature.com
In recent years ample studies have reported that intranasal administration of the
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …

Intranasal oxytocin and vasopressin modulate divergent brainwide functional substrates

A Galbusera, A De Felice, S Girardi… - …, 2017 - nature.com
The neuropeptides oxytocin (OXT) and vasopressin (AVP) have been identified as
modulators of emotional social behaviors and associated with neuropsychiatric disorders …

Oro-mucosal administration of oxytocin using medicated lollipops alters social attention, similar to intranasal and lingual routes: Implications for therapeutic use

D Xu, Q Li, Q Zhuang, Y Zhang, S Yao… - Frontiers in …, 2022 - frontiersin.org
A key functional effect of intranasal administration of the neuropeptide oxytocin is on top-
down control of social attention. However, an oro-mucosal administration route may be …

Sex differences in the neural and behavioral response to intranasal oxytocin and vasopressin during human social interaction

JK Rilling, AC DeMarco, PD Hackett, X Chen… - …, 2014 - Elsevier
Both oxytocin (OT) and vasopressin (AVP) are known to modulate social behavior, and
dysfunction in both systems has been postulated as a potential cause of certain psychiatric …

Statistical and methodological considerations for the interpretation of intranasal oxytocin studies

H Walum, ID Waldman, LJ Young - Biological psychiatry, 2016 - Elsevier
Over the last decade, oxytocin (OT) has received focus in numerous studies associating
intranasal administration of this peptide with various aspects of human social behavior …

Oxytocin effects on the human brain: findings, questions, and future directions

O Weisman, R Feldman - Biological Psychiatry, 2013 - biologicalpsychiatryjournal.com
Since the discovery that intranasal administration of neuro-peptides can have a direct impact
on the human brain, extant research has been devoted to understanding the effects of …