Liver X receptors (LXRs) are implicated in the regulation of cholesterol homeostasis,
inflammatory response and atherogenesis. Administration of LXR agonists inhibits the …

Background—The nuclear liver X receptor-α (LXR-α) has been implicated in the regulation
of intracellular cholesterol homeostasis, inflammatory response, and atherosclerosis …

Objective—Complications of atherosclerotic cardiovascular disease due to elevated blood
cholesterol levels are the major cause of death in the Western world. The liver X receptors …

Liver X receptors (LXRs) α and β are transcriptional regulators of cholesterol homeostasis
and potential targets for the development of antiatherosclerosis drugs. However, the specific …

The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate
sterol metabolism and inflammation. We sought to identify previously unknown genes …

The liver X receptors (LXRs) are sterol-responsive transcription factors that regulate the
expression of genes involved in cholesterol homeostasis. Studies in murine models have …

The liver X receptors LXRα and LXRβ play critical roles in maintaining lipid homeostasis by
functioning as transcription factors that regulate genetic networks controlling the transport …

Recent studies have identified the liver X receptors (LXRα and LXRβ) as important
regulators of cholesterol metabolism and transport. LXRs control transcription of genes …

Nuclear hormone receptors liver X receptor (LXRα and LXRβ) ligands are attractive
approaches for the treatment of dyslipidemia and atherosclerosis. To further elucidate the …

Liver X receptor (LXR) nuclear receptors regulate the expression of genes involved in whole
body cholesterol trafficking, including absorption, excretion, catabolism, and cellular efflux …