Objective: Decreased oxygen supply is generally accepted as the primary cause of muscle
dysfunction in patients with peripheral arterial occlusive disease (PAOD) and intermittent …

Purpose: We used 31P magnetic resonance spectroscopy (MRS) and near-infrared
spectroscopy (NIRS) as a means of quantifying abnormalities in calf muscle oxygenation …

1. We set out to define abnormalities of oxidative ATP synthesis, cellular proton efflux and
the efficiency of ATP usage in gastrocnemius muscle of patients with claudication due to …

RATIONALE AND OBJECTIVES. The aim of the authors' prospective study was to explore
therapy-induced changes of muscular metabolism in arterial occlusive disease (AOD) …

BACKGROUND: The treadmill exercise test is the most important examination of the
functional ability of patients with intermittent claudication or leg pain during exercise, but it …

The biochemical effects of peripheral vascular disease on skeletal muscle have not been
characterized precisely because of the lack of satisfactory noninvasive analytic methods. 31 …

Energy metabolism of calf muscle was assessed non‐invasively by phosphorus (31P) NMR
spectroscopy in eleven patients with symptomatic arterial occlusion and in seven matched …

OBJECTIVE: To identify differences in postexercise phosphocreatine (PCr) recovery, an
index of mitochondrial function, in diabetic patients with and without lower extremity …

The effect of a graded exercise protocol on phosphorus-31 magnetic resonance (MR)
spectroscopy of calf skeletal muscle in nine healthy (control) subjects and 16 patients with …

Background Clinical assessments of peripheral artery disease (PAD) severity are insensitive
to pathophysiological changes in muscle tissue oxygenation and energy metabolism distal …