[HTML][HTML] CRISPR-Cas and its wide-ranging applications: From human genome editing to environmental implications, technical limitations, hazards and bioethical …

R Piergentili, A Del Rio, F Signore, F Umani Ronchi… - Cells, 2021 - mdpi.com
The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms,
including man. During the years this technique has been applied in several fields, such as …

[HTML][HTML] The ethical impact of new genetic editing technologies

SD Bergel - Revista Bioética, 2017 - SciELO Brasil
The discovery of the CRISPR/CAS 9 genetic engineering technique opens up important new
horizons for scientific research. The ethical, legal and social problems that can be applied to …

Gene Editing Using CRISPR/Cas9 System: Methods and Applications

B Arthi, AV Anand, N Senthilkumar… - CRISPR and Plant … - taylorfrancis.com
Genome editing is a modification of genes in the DNA sequence. These techniques are
used in both in vitro and in vivo models to modify their genomic sequence. Genomic editing …

The revolutionary genome editor: CRISPR-Cas9 systems

G Spade - 2023 - digitalcommons.liberty.edu
Genetic engineering is the modification of an organism's genetic material to alter its traits
through adding, deleting, or changing specific genes. CRISPR-Cas9 systems are …

Application of CRISPR/Cas9 system for developing and studying cellular models of inherited disease

KR Valetdinova - Genes & Cells, 2016 - journals.eco-vector.com
Currently, more than 4500 diseases classified as an inherited diseases. Most forms of
human inherited diseases are caused by gene mutations. Given to the development of new …

[PDF][PDF] CRISPR-Cas Fonksiyonel Genetik Tarama: Geleneksel Derleme

HG Kara, B Kosova, E Doğan… - Türkiye Klinikleri. Tip …, 2022 - researchgate.net
Prokaryotlara ait savunma mekanizması bileşenleri kullanılarak geliştirilen düzenli
aralıklarla bölünmüş kısa palindromik tekrar kümeleri [clustered regularly interspaced …

CRISPR-Cas9, a new chance for somatic gene therapy

B Jordan - Medecine Sciences: M/S, 2015 - europepmc.org
Targeted modification of genes (" gene editing") is made much easier by the recently
developed CRISPR-Cas9 system. This has raised alarm about possible uses of this …

Application of CRISPR-Based Technology in Medical Research and Disease Treatment

Z Zhang, P Wang, JL Liu - CRISPR: A Machine-Generated Literature …, 2022 - Springer
Seeking treatments for human diseases is an important goal and motivation of biomedical
research. Over thousands of years, humans have gradually formed a series of treatment …

The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine

Y Yang, Y Huang - Animal models and experimental medicine, 2019 - Wiley Online Library
Abstract A Chinese scientist, Jiankui He, and his creation of the world's first genetically
altered baby made headlines recently. As a newly developed gene‐editing technique, the …

CRISPR mediated genome engineering and its application in industry

S Kaboli, H Babazada - Current Issues in Molecular Biology, 2018 - mdpi.com
The CRISPR (clustered regularly interspaced short palindromic repeat)/Cas9 (CRISPR-
associated nuclease 9) method has been dramatically changing the field of genome …