Bile acid profiles are distinct among patients with different etiologies of chronic liver disease

C Sang, X Wang, K Zhou, T Sun, H Bian… - Journal of proteome …, 2021 - ACS Publications
A significant increase of bile acid (BA) levels has been recognized as a general metabolic
phenotype of diverse liver diseases. Monitoring of BA profiles has been proposed for …

Serum bile acids are associated with pathological progression of hepatitis B-induced cirrhosis

X Wang, G Xie, A Zhao, X Zheng, F Huang… - Journal of proteome …, 2016 - ACS Publications
Recent metabonomic studies have identified an important role of bile acids in patients with
liver cirrhosis. Serum bile acids, such as glycocholate (GCA), glycochenodeoxycholate …

Profiling of serum bile acids in a healthy Chinese population using UPLC–MS/MS

G Xie, Y Wang, X Wang, A Zhao, T Chen… - Journal of proteome …, 2015 - ACS Publications
Bile acids (BAs) are a group of important physiological agents for cholesterol metabolism,
intestinal nutrient absorption, and biliary secretion of lipids, toxic metabolites, and …

Urinary bile acids as biomarkers for liver diseases II. Signature profiles in patients

SPR Bathena, R Thakare, N Gautam… - Toxicological …, 2015 - academic.oup.com
Hepatobiliary diseases result in the accumulation of bile acids (BAs) in the liver, systemic
blood, and other tissues leading to an unfavorable prognosis. The BA profile was …

Urinary bile acids as biomarkers for liver diseases I. Stability of the baseline profile in healthy subjects

SPR Bathena, R Thakare, N Gautam… - Toxicological …, 2015 - academic.oup.com
The role of bile acids (BAs) as biomarkers for liver injury has been proposed for decades.
However, the large inter-and intra-individual variability of the BA profile has prevented its …

The potential of bile acids as biomarkers for metabolic disorders

C Yin, R Zhong, W Zhang, L Liu, L Chen… - International Journal of …, 2023 - mdpi.com
Bile acids (BAs) are well known to facilitate the absorption of dietary fat and fat-soluble
molecules. These unique steroids also function by binding to the ubiquitous cell membranes …

Assessment of serum bile acid profiles as biomarkers of liver injury and liver disease in humans

L Luo, J Aubrecht, D Li, RL Warner, KJ Johnson… - PloS one, 2018 - journals.plos.org
To assess the potential of individual bile acids (IBA) and their profiles as mechanistic
biomarkers of liver injury for humans in real world situations, we interrogated samples …

Altered bile acid glycine: taurine ratio in the progression of chronic liver disease

T Chen, K Zhou, T Sun, C Sang… - … of gastroenterology and …, 2022 - Wiley Online Library
Abstract Background and Aim The onset and progression of chronic liver disease (CLD) is a
multistage process spanning years or several decades. Some bile acid (BA) features are …

[PDF][PDF] Metabolic profiling of bile acids in the urine of patients with alcohol‐associated liver disease

L He, V Vatsalya, X Ma, J Zhang, X Yin… - Hepatology …, 2021 - Wiley Online Library
Bile acids (BAs) play important functions in the development of alcohol‐associated liver
disease (ALD). In the current study, urine BA concentrations in 38 patients with well …

Circulating bile acids as biomarkers for disease diagnosis and prevention

L Qi, Y Chen - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Abstract Context Bile acids (BAs) are pivotal signaling molecules that regulate energy
metabolism and inflammation. Recent epidemiological studies have reported specific …