Cancer is an evolutionary disease, containing the hallmarks of an asexually reproducing
unicellular organism subject to evolutionary paradigms. Pancreatic ductal adenocarcinoma …

Pancreatic ductal adenocarcinoma (PDAC), already among the deadliest epithelial
malignancies, is rising in both incidence and contribution to overall cancer deaths. Decades …

With 5-year survival rates remaining constant at 6% and rising incidences associated with
an epidemic in obesity and metabolic syndrome, pancreatic ductal adenocarcinoma (PDAC) …

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the
United States with a median survival of< 6 mo and a dismal 5-yr survival rate of 3%–5%. The …

Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5-year survival rate of
approximately 9%. An improved understanding of PDAC initiation and progression is …

Pancreatic ductal adenocarcinoma is an aggressive and devastating disease, which is
characterized by invasiveness, rapid progression and profound resistance to treatment …

Pancreatic Ductal Adenocarcinoma (PDAC) is the fourth most common cause of cancer-
related death and is the most lethal of common malignancies with a five-year survival rate …

Patients with pancreatic ductal adenocarcinoma (PDA) have a poor prognosis despite new
treatments; approximately 7% survive for 5 years. Although there have been advances in …

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers. Significant
efforts have largely defined major genetic factors driving PDAC pathogenesis and …

Pancreatic cancer is an almost universally lethal disease and despite extensive research
over the last decades, this has not changed significantly. Nevertheless, much progress has …