Maotai ameliorates diethylnitrosamine-initiated hepatocellular carcinoma formation in mice

X Yi, L Long, C Yang, Y Lu, M Cheng - PloS one, 2014 - journals.plos.org
Consumption of alcohol is closely related to liver disease, such as hepatic fibrosis or even
hepatocellular carcinoma (HCC). However, epidemiological and experimental studies …

Differential effects between Maotai and ethanol on hepatic gene expression in mice: possible role of metallothionein and heme oxygenase-1 induction by Maotai

J Liu, ML Cheng, JZ Shi, Q Yang, J Wu… - Experimental …, 2006 - journals.sagepub.com
Alcohol is a risk factor for liver fibrosis and hepatocellular carcinoma. On the other hand,
light alcoholic beverage consumption is believed to be beneficial because of the effects of …

Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice

S Fuentes-Hernández, BR Alarcón-Sánchez… - Toxicology and applied …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) arises after a long period of exposition to etiological factors
that might be either independent or collectively contributing. Several rodent models …

[PDF][PDF] Sesame oil mitigates initiation stage of diethynitrosamine hepatocarcinogenesis in rats.

AAA Mokh, DH Abdelhady, EW Ghazy… - 2019 - researchgate.net
Diethylnitrosamine (DEN) induced hepatocarcinogenesis in experimental animals through
triggering reactive oxygen species (ROS) release and subsequent induction of oxidative …

Effect of alcohol on diethylnitrosamine-induced hepatic toxicity: Critical role of ROS, lipid accumulation, and mitochondrial dysfunction

Q Sun, Z Long, H Wu, Y Liu, L Wang, X Zhang… - Experimental and …, 2015 - Elsevier
Hepatocellular carcinoma (HCC) is the fifth most common cancer in men and the seventh in
women worldwide. Chronic heavy alcohol consumption is a major risk factor for the …

Suppressive effects of thymoquinone on the initiation stage of diethylnitrosamine hepatocarcinogenesis in rats

S Ibrahim, SA Fahim, SA Tadros… - Journal of Biochemical …, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer‐related death
globally. Chemoprevention is the most effective technique for reducing HCC incidence …

Gehua Jiecheng decoction inhibits diethylnitrosamine-induced hepatocellular carcinoma in mice by improving tumor immunosuppression microenvironment

C Cheng, Q Shou, J Lang, L Jin, X Liu… - Frontiers in …, 2020 - frontiersin.org
Gehua Jiecheng Decoction (GHJCD), a famous traditional Chinese medicine, has been
used in the prevention and treatment of precancerous lesion of liver cancer, but its active …

RETRACTED: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes

S Majumder, S Roy, T Kaffenberger, B Wang… - Cancer research, 2010 - AACR
Metallothioneins (MT) are potent scavengers of free radicals that are silenced in primary
hepatocellular carcinomas (HCC) of human and rodent origin. To examine whether loss of …

Chronic alcohol consumption promotes diethylnitrosamine-induced hepatocarcinogenesis via immune disturbances

G Yan, X Wang, C Sun, X Zheng, H Wei, Z Tian… - Scientific reports, 2017 - nature.com
Chronic alcohol consumption increases the risk of hepatocellular carcinoma (HCC).
However, little is known about the potential immunological mechanisms by which ethanol …

Chronic ethanol feeding accelerates hepatocellular carcinoma progression in a sex‐dependent manner in a mouse model of hepatocarcinogenesis

E Brandon‐Warner, TL Walling… - Alcoholism: Clinical …, 2012 - Wiley Online Library
Background: Chronic ethanol consumption increases the risk of hepatic cirrhosis and
hepatocellular carcinoma (HCC). While sex differences exist in susceptibility to ethanol …