The histologic spectrum of soft tissue spindle cell tumors with NTRK3 gene rearrangements

AJ Suurmeijer, BC Dickson, D Swanson… - Genes …, 2019 - Wiley Online Library
ABSTRACT NTRK3‐rearranged tumors other than infantile fibrosarcomas (IFSs) harboring
the canonical ETV6‐NTRK3 fusions are uncommon, and include mainly inflammatory …

ALK-1 expression in inflammatory myofibroblastic tumor of the urinary bladder

T Tsuzuki, C Magi-Galluzzi… - The American journal of …, 2004 - journals.lww.com
Inflammatory myofibroblastic tumor (IMT) of the bladder is an uncommon myofibroblastic
spindle cell proliferation. Because of its cytologic features and infiltrative nature, it may be …

Crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumours with and without anaplastic lymphoma kinase gene alterations (European …

P Schöffski, J Sufliarsky, H Gelderblom… - The Lancet …, 2018 - thelancet.com
Background An inflammatory myofibroblastic tumour (IMFT) is a rare mesenchymal
neoplasm characterised by anaplastic lymphoma kinase (ALK) gene rearrangements. We …

[HTML][HTML] Utility of ALK-1 protein expression and ALK rearrangements in distinguishing inflammatory myofibroblastic tumor from malignant spindle cell lesions of the …

WR Sukov, JC Cheville, AW Carlson, BM Shearer… - Modern pathology, 2007 - Elsevier
Inflammatory myofibroblastic tumor of the urinary bladder is an unusual spindle cell
neoplasm that displays cytologic atypia, infiltrative growth and mitotic activity mimicking …

[HTML][HTML] Anaplastic lymphoma kinase (ALK 1) staining and molecular analysis in inflammatory myofibroblastic tumours of the bladder: a preliminary clinicopathological …

A Freeman, N Geddes, P Munson, J Joseph, P Ramani… - Modern Pathology, 2004 - Elsevier
Inflammatory myofibroblastic tumours (IMFT) may arise at any anatomical site, including
lung, soft tissues, retroperitoneum and bladder. Although morphologically similar, these …

Inflammatory myofibroblastic tumor: the continued definition of one type of so-called inflammatory pseudotumor

LP Dehner - The American journal of surgical pathology, 2004 - journals.lww.com
When one enters the phrase ''inflammatory myofibroblastic tumor''(IMT) into PubMed, one
obtains more than 200 citations dating from the 1980s; one of the first studies using this …

[HTML][HTML] Superficial ALK-rearranged myxoid spindle cell neoplasm: a cutaneous soft tissue tumor with distinctive morphology and immunophenotypic profile

JK Dermawan, EM Azzato, JR Goldblum, BP Rubin… - Modern Pathology, 2021 - Elsevier
Gene rearrangements involving the anaplastic lymphoma kinase (ALK) receptor tyrosine
kinase gene have been identified in various neoplasms, including inflammatory …

Inflammatory myofibroblastic tumor in children: clinical review with anaplastic lymphoma kinase, Epstein-Barr virus, and human herpesvirus 8 detection analysis

F Mergan, F Jaubert, F Sauvat, O Hartmann… - Journal of pediatric …, 2005 - Elsevier
BACKGROUND/PURPOSE: Inflammatory myofibroblastic tumor (IMT) is considered as an
intermediate neoplasm that may present malignant features. Differential diagnosis with other …

Paediatric and adult soft tissue sarcomas with NTRK1 gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern

F Haller, J Knopf, A Ackermann, M Bieg… - The Journal of …, 2016 - Wiley Online Library
Neoplasms with a myopericytomatous pattern represent a morphological spectrum of
lesions encompassing myopericytoma of the skin and soft tissue, angioleiomyoma …

Anaplastic lymphoma kinase proteins in growth control and cancer

K Pulford, SW Morris, F Turturro - Journal of cellular physiology, 2004 - Wiley Online Library
The normal functions of full‐length anaplastic lymphoma kinase (ALK) remain to be
completely elucidated. Although considered to be important in neural development, recent …