The SMEDDS are the isotropic mixture of oil, surfactant and co-surfactant. SMEDDS solve
the problem of all BCS class of drug such as solubility, high molecular weight, pre systemic …

Several methods are being employed to improve the oral bioavailability of lipophilic drugs
like using inert lipid vehicles such as Oils, Surfactant dispersions, Self Microemulsifying …

Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a
major challenge to modern drug delivery system because of their low bioavailability. The …

Oral route is the easiest and most convenient route of drug administration, being non
invasive and cost effective, thereby leading worldwide drug delivery market. But major …

The improvement of oral bioavailability of poorly water soluble drug can be considered as
one of the greatest challenges in drug formulation. In recent years today, up to 90% of all …

Abstract About 70-75% of drugs is taken orally and is found not to be as useful as desired. A
self-micro emulsifying drug delivery system (SMEDDS) is a drug delivery system that uses a …

The oral route is most preferred one as there is ease of administration and it is a painless
approach. This favored route is restricted to those drug molecules that are absorbent over …

ABSTRACT Around 40-60% of potential drugs in the pharmaceutical market are lipophilic in
nature due to the low aqueous solubility and low permeability and thereby facing problems …

Background: More than 60% of the new drug molecules are lipophilic in nature. Low
aqueous solubility and thus poor bioavailability is the main issue for these drugs for …