Left ventricular dysfunction associated with brain death: results from the Donor Heart Study

KK Khush, D Malinoski, H Luikart, B Wayda, T Groat… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Left ventricular dysfunction in potential donors meeting brain death criteria
often results in nonuse of donor hearts for transplantation, yet little is known about its …

Temporal changes in left ventricular systolic function and use of echocardiography in adult heart donors

XI Borbely, V Krishnamoorthy, S Modi… - Neurocritical care, 2015 - Springer
Background One reason for refusal of donor hearts is the development of left ventricular
systolic dysfunction, a condition reported to occur in up to 42% of adults with brain death …

Brain death and donor heart dysfunction: implications in cardiac transplantation

E Apostolakis, H Parissis… - Journal of cardiac …, 2010 - Wiley Online Library
Aim: In this article, the hemodynamic, humoral, and immunological perturbations following
brain death (BD) are going to be discussed in a stepwise manner. Materials and Methods …

Ventricular dysfunction associated with brain trauma is cause for exclusion of young heart donors

M Godino, M Lander, A Cacciatore… - Transplantation …, 2010 - Elsevier
OBJECTIVE: Ventricular dysfunction (VD) in the context of brain death (BD) is one medical
cause that may be reversed to extend the range of donors for cardiac transplant programs …

[HTML][HTML] Long-term transplant outcomes of donor hearts with left ventricular dysfunction

A Sibona, KK Khush, UE Oyoyo, TP Martens… - The Journal of thoracic …, 2019 - Elsevier
Objective Despite small single-center reports demonstrating acceptable outcomes using
donor hearts with left ventricular dysfunction, 19% of potential donor hearts are currently …

Outcomes after transplantation of donor hearts with improving left ventricular systolic dysfunction

S Madan, O Saeed, P Vlismas, I Katsa, SR Patel… - Journal of the American …, 2017 - jacc.org
Background: Left ventricular systolic dysfunction (LVSD) accounts for almost 25% of
nonacceptance of potential donor hearts. Previous smaller, single-center studies showed …

[HTML][HTML] Left ventricular dysfunction in potential heart donors and its influence on recipient outcomes

J Oras, R Doueh, E Norberg, B Redfors… - The Journal of thoracic …, 2020 - Elsevier
Objectives New onset of left ventricular (LV) dysfunction in organ donors is frequent and
considered as a contraindication for utilization of the heart. However, such dysfunction might …

Right ventricular function in the donor heart

SWH Kendall, HB Bittner, DS Peterseim… - European journal of …, 1997 - academic.oup.com
OBJECTIVES: Early morbidity and mortality post cardiac transplantationis frequently caused
by right ventricular failure; this is usuallyattributed to an elevated pulmonary vascular …

Donor brain death mechanisms and outcomes after heart transplantation

O Cohen, DJ De La Zerda, R Beygui, D Hekmat… - Transplantation …, 2007 - Elsevier
We sought to explore whether the cause of donor brain death influenced recipient outcomes
after cardiac transplantation. In retrospect, 358 consecutive donors provided cardiac …

Brain death and its impact on the donor heart—lessons from animal models

MJ Wilhelm, J Pratschke, IA Laskowski… - The Journal of Heart …, 2000 - jhltonline.org
The number of patients waiting for organ transplantation and the number of donor organs
available have progressively diverged. Several different efforts are currently being …