Early effects of mirtazapine on emotional processing

D Arnone, J Horder, PJ Cowen, CJ Harmer - Psychopharmacology, 2009 - Springer
Background Acute administration of selective serotonin and noradrenaline re-uptake
blockers to healthy volunteers affects the processing of emotional information but it is not …

Dissociable effects of acute antidepressant drug administration on subjective and emotional processing measures in healthy volunteers

CJ Harmer, J Heinzen, U O'Sullivan, RA Ayres… - …, 2008 - Springer
Background We have previously shown that single doses of serotonin-selective and
noradrenaline-selective antidepressant agents produce positive biases in measures of …

A single dose of mirtazapine modulates neural responses to emotional faces in healthy people

NB Rawlings, R Norbury, PJ Cowen, CJ Harmer - Psychopharmacology, 2010 - Springer
Rationale Single-dose administration of selective serotonin and noradrenaline reuptake
blockers has been shown to alter emotional processing in both behavioral and fMRI studies …

Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition

CJ Harmer, NC Shelley, PJ Cowen… - American Journal of …, 2004 - Am Psychiatric Assoc
OBJECTIVE: Antidepressants that inhibit the reuptake of serotonin (SSRIs) or
norepinephrine (SNRIs) are effective in the treatment of disorders such as depression and …

Effect of acute antidepressant administration on negative affective bias in depressed patients

CJ Harmer D Phil, U O'Sullivan… - American Journal of …, 2009 - Am Psychiatric Assoc
Objective: Acute administration of an antidepressant increases positive affective processing
in healthy volunteers, an effect that may be relevant to the therapeutic actions of these …

Serotonin and emotional processing: does it help explain antidepressant drug action?

CJ Harmer - Neuropharmacology, 2008 - Elsevier
There is growing interest in the effects of antidepressant drug treatment on measures of
emotional processing. Such actions may help us understand the role of monoamines in …

Mirtazapine compared with paroxetine in major depression

O Benkert, A Szegedi, R Kohnen - Journal of Clinical Psychiatry, 2000 - psychiatrist.com
Background: The aim was to compare the efficacy and tolerability of mirtazapine with those
of paroxetine. Method: 275 outpatients with a diagnosis of major depressive episode (DSM …

Short-term antidepressant treatment modulates amygdala response to happy faces

R Norbury, MJ Taylor, S Selvaraj, SE Murphy… - …, 2009 - Springer
Rationale We have previously demonstrated that antidepressant medication facilitates the
processing of positive affective stimuli in healthy volunteers. These early effects of …

Acute 5-HT reuptake blockade potentiates human amygdala reactivity

KL Bigos, BG Pollock, HJ Aizenstein… - …, 2008 - nature.com
Abstract Variability in serotonin (5-HT) function is associated with individual differences in
normal mood and temperament, as well as psychiatric illnesses, all of which are influenced …

A single dose of mirtazapine attenuates neural responses to self-referential processing

E Komulainen, R Heikkilä… - Journal of …, 2016 - journals.sagepub.com
Increased self-focus is a core factor in the psychopathology of depression. Cortical midline
structures (CMS) are implicated in the neurobiology of self, depression and antidepressant …