Ethanol extract of peanut sprout induces Nrf2 activation and expression of antioxidant and detoxifying enzymes in human dermal fibroblasts: Implication for its …

JY Choi, DI Choi, JB Lee, SJ Yun… - Photochemistry and …, 2013 - Wiley Online Library
A peanut sprout is known to contain a significant level of resveratrol, which was reported to
have beneficial effects in our body due to its antioxidant activities. The purpose of this study …

Pterostilbene protects against UVB-induced photo-damage through a phosphatidylinositol-3-kinase-dependent Nrf2/ARE pathway in human keratinocytes

H Li, N Jiang, B Liang, Q Liu, E Zhang, L Peng… - Redox …, 2017 - Taylor & Francis
ABSTRACT Objective: Ultraviolet B (UVB) irradiation is the initial etiological factor for various
skin disorders, including erythema, sunburn, photoaging, and photocarcinogenesis …

Effects of natural antioxidants on phospholipid and ceramide profiles of 3D-cultured skin fibroblasts exposed to UVA or UVB radiation

A Gęgotek, W Łuczaj, E Skrzydlewska - Antioxidants, 2021 - mdpi.com
Ultraviolet (UV) radiation is one of the primary factors responsible for disturbances in human
skin cells phospholipid metabolism. Natural compounds that are commonly used to protect …

[HTML][HTML] Low-dose radiation activates Nrf1/2 through reactive species and the Ca2+/ERK1/2 signaling pathway in human skin fibroblast cells

EK Lee, JA Kim, SJ Park, JK Kim, K Heo, KM Yang… - BMB …, 2013 - ncbi.nlm.nih.gov
In the current study, we explored the effect of LDR on the activation of Nrfs transcription
factor involved in cellular redox events. Experiments were carried out utilizing 0.05 and 0.5 …

Cynaropicrin attenuates UVB-induced oxidative stress via the AhR–Nrf2–Nqo1 pathway

K Takei, A Hashimoto-Hachiya, M Takahara, G Tsuji… - Toxicology Letters, 2015 - Elsevier
Due to its antioxidant and anti-inflammatory activities, artichoke (Cynara scolymus) has been
used as folk medicine to treat various diseases. Cynaropicrin (Cyn), a sesquiterpene …

Possible involvement of dermal fibroblasts in modulating Nrf2 signaling in epidermal keratinocytes

Y Tsuruta, Y Katsuyama, Y Okano, T Ozawa… - Biological and …, 2023 - jstage.jst.go.jp
Epidermal keratinocytes protect themselves by cooperating with neighboring cells against
internal and external stresses, which leads not only to the maintenance of cell homeostasis …

Reconstructed human skin: From photodamage to sunscreen photoprotection and anti-aging molecules

C Vioux-Chagnoleau, F Lejeune, J Sok… - Journal of …, 2006 - Elsevier
BACKGROUND: Acute or repetitive sun exposure has been shown to be responsible for
various deletorious consequences such as sunburn reaction, photoaging and photocancers …

α-Melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin

A Kokot, D Metze, N Mouchet, MD Galibert… - …, 2009 - academic.oup.com
Human skin is constantly exposed to UV light, the most ubiquitous environmental stressor.
Here, we investigated the expression and regulation of Nrf1-3, transcription factors crucially …

Photo-protective effect of sargachromenol against UVB radiation-induced damage through modulating cellular antioxidant systems and apoptosis in human …

PMDJ Fernando, MJ Piao, SRKM Hewage… - Environmental …, 2016 - Elsevier
The aim of this study was to evaluate the photo-preventive effects of sargachromenol (SC)
against ultraviolet B (UVB)-induced oxidative stress in human keratinocytes via assessing …

[HTML][HTML] NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells

F Gruber, H Mayer, B Lengauer, V Mlitz… - The FASEB …, 2010 - ncbi.nlm.nih.gov
Abstract Long-wavelength ultraviolet (UVA-1) radiation causes oxidative stress that modifies
cellular molecules. To defend themselves against noxious oxidation products, skin cells …