The anatomical distribution of serotonin-1 receptors in human postmortem brain tissue was
studied by quantitative light microscopic autoradiography.[3 H] Serotonin was used to label …

Degenerate primers, suitable for polymerase chain reaction studies and based on the
conserved structure of G protein-coupled receptors, were used to isolate cDNA clones …

Serotonin [5-hydroxytryptamine (5-HT)] is a neuromodulator that mediates a wide range of
physiological functions by activating multiple receptors. Using a strategy based on amino …

In the presence of 1 μM (±)‐pindolol [to block 5‐hydroxytryptamine (5‐HT, serotonin) 5‐
HT1A and 5‐HT1B receptors] and 100 nM mesulergine (to block 5‐HT1C receptors), 2.0 nM …

The field of serotonin (5HT) receptor pharmacology has been at least as dramatically altered
by the advent of molecular neurobiology and recombinant DNA techniques as has any other …

We developed and characterized 14 polyclonal antibodies against peptides whose
sequences were predicted from the type 3 serotonin receptor subunit A (5-HT3R-A) cDNA …

A short overview is given of the evidence supporting the existence of subtypes of 5-HT1
receptors. As 5-HT1 receptors were first described using radioligand binding studies, a brief …

The regional distribution of the mRNA encoding the 5-HT 1A serotonin receptor (whose
selective agonists are potential anxiolytic and antidepressant drugs) was investigated in rat …

The 5-HT5A receptor is a member of a new subfamily of serotonin [5-hydroxytryptamine (5-
HT)] receptors recently cloned from the human and rodent brain. The role of this receptor in …

[3H] 5-HT revealed the presence of serotonin receptors in cultured rat sensory neurons.[3H]
5-CT binding was inhibited by cyanopindolol with an IC50 of 0.87±0.30 nM, suggesting the …