Introduction The tobacco-specific nitrosamines (TSNAs) are an important group of
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …

Introduction: Tobacco smoke contains more than 7,000 chemicals, including known
carcinogens, such as tobacco-specific nitrosamines (TSNAs). TSNA levels in cigarettes vary …

Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N′-nitroso nornicotine (NNN), N′-nitroso anabasine (NAB) and N …

The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a
metabolite of the tobacco-specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl)-1 …

Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …

Carcinogenic tobacco-specific nitrosamines (TSNAs) such as 4-(methylnitrosamino)-1-(3-
pyridyl)-1-butanone (NNK) are found only in tobacco and derived products. Food and Drug …

Tobacco-specific nitrosamines (TSNAs) have been previously implicated as a source of
carcinogenicity in tobacco and cigarette smoke. Accurate quantification of these chemicals is …

Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N-nitrosonornicotine (NNN), N-nitrosoanabasine (NAB) and N …

Tobacco-specific nitrosamines (TSNAs) comprise one of the major classes of carcinogenic
compounds in mainstream cigarette smoke. As part of collaborative efforts between the …

ABSTRACT A liquid chromatography tandem mass spectrometry (LC/MS/MS) method was
developed and validated for the determination of five total tobacco‐specific N‐nitrosamines …