An improved method has been developed for the determination of the four major tobacco-
specific nitrosamines (TSNA) in mainstream cigarette smoke. The new method offers …

Tobacco-specific nitrosamines are a group of carcinogens formed from nicotine and related
tobacco alkaloids. Two of these compounds, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone …

More than 24 N-nitrosamine compounds contribute to the total N-nitrosamine (TNA) burden
monitored routinely to assess human exposure to this important group of known and …

(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and its glucuronides (sum of which is
denoted as total NNAL) are metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone …

It has been estimated that one in every five cancer deaths worldwide are related to tobacco
use. According to the IARC, 10 polycyclic aromatic hydrocarbons (PAH) and 8 tobacco …

(Methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK) is a carcinogenic nitrosamine
produced upon curing tobacco. It is present in tobacco smoke and undergoes metabolism to …

Bidi cigarettes, or bidis, are a tobacco product that originated in India and have been gaining
popularity in the USA during the past few years, particularly with adolescents. As with …

Importance Transitions between e-cigarettes and cigarettes are common among tobacco
users, but empirical evidence on the health outcomes of switching tobacco products is …

9) for smokers and 0.9±2.3 (= 8) for nonsmokers. Mean adduct levels in tracheobronchus
were 16±18 (= 4) for smokers and 0.9±1.7 (= 4) for nonsmokers. These are the first …

Introduction: Researchers have recently suggested that nicotine and carcinogen exposure
as measured by biomarkers such as cotinine and NNAL (4-(methylnitrosamino)-1-(3-pyridyl) …