Upregulation of miR-146a contributes to the suppression of inflammatory responses in LPS-induced acute lung injury

Z Zeng, H Gong, Y Li, K Jie, C Ding… - Experimental lung …, 2013 - Taylor & Francis
Despite the critical role of microRNA in inflammatory response, little is known about its
function in inflammation-induced Acute Lung Injury (ALI)/Acute Respiratory Distress …

[HTML][HTML] MicroRNA-106a provides negative feedback regulation in lipopolysaccharide-induced inflammation by targeting TLR4

J Yang, Y Chen, K Jiang, Y Yang, G Zhao… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
Acute lung injury (ALI) is a common clinical disease with high incidence and mortality rate,
which is characterized by severe inflammatory response and tissues damage. MicroRNAs …

Depleting microRNA-146a-3p attenuates lipopolysaccharide-induced acute lung injury via up-regulating SIRT1 and mediating NF-κB pathway

Y Yang, L Li - Journal of Drug Targeting, 2021 - Taylor & Francis
Objective The role of microRNAs (miRs) in acute lung injury (ALI) has been discussed. This
study is to uncover the effects of miR-146a-3p/Sirtuin-1 (SIRT1)/Nuclear factor-kappa B (NF …

MiR-216a alleviates LPS-induced acute lung injury via regulating JAK2/STAT3 and NF-κB signaling

F Kong, Y Sun, W Song, Y Zhou, S Zhu - Human cell, 2020 - Springer
MicroRNAs (miRNAs) play an important role in the progression of acute lung injury (ALI) and
acute respiratory distress syndrome (ARDS). Till now, little is known about the role of miR …

[HTML][HTML] MicroRNA-21 inhibits lipopolysaccharide-induced acute lung injury by targeting nuclear factor-κB

WD Zhu, J Xu, M Zhang, TM Zhu… - Experimental and …, 2018 - spandidos-publications.com
Acute lung injury (ALI) is a frequent, but severe complication following sepsis in patients with
critical illness. The present study aimed to investigate the potential role of microRNA-21 …

[HTML][HTML] Downregulation of TLR4 by miR-181a provides negative feedback regulation to lipopolysaccharide-induced inflammation

K Jiang, S Guo, T Zhang, Y Yang, G Zhao… - Frontiers in …, 2018 - frontiersin.org
Acute lung injury (ALI) is a progressive clinical disease with a high mortality rate, and
characterized by an excessive uncontrolled inflammatory response. MicroRNAs (miRNAs) …

[HTML][HTML] MicroRNA-92a antagonism attenuates lipopolysaccharide (LPS)-induced pulmonary inflammation and injury in mice through suppressing the PTEN/AKT/NF …

L Fu, P Zhu, S Qi, C Li, K Zhao - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Overwhelming lung inflammation is a key feature of acute lung injury (ALI). MicroRNAs
(miRNAs) have been implicated in the regulation diverse cellular processes including the …

MicroRNAs are dynamically regulated and play an important role in LPS-induced lung injury

ZG Cai, SM Zhang, Y Zhang, YY Zhou… - Canadian journal of …, 2012 - cdnsciencepub.com
Acute lung injury is characterized by an increase of inflammatory reaction and severe lung
edema. Even if there have been great advances in the identification of genes and signaling …

[HTML][HTML] MicroRNA‑223 attenuates LPS‑induced inflammation in an acute lung injury model via the NLRP3 inflammasome and TLR4/NF‑κB signaling pathway via …

Y Yan, K Lu, T Ye, Z Zhang - … Journal of Molecular …, 2019 - spandidos-publications.com
Acute lung injury (ALI) and the more severe acute respiratory distress syndrome are
common and complex inflammatory lung diseases. MicroRNAs (miRs) have emerged as …

Macrophage micro-RNA-155 promotes lipopolysaccharide-induced acute lung injury in mice and rats

W Wang, Z Liu, J Su, WS Chen… - … of Physiology-Lung …, 2016 - journals.physiology.org
Micro-RNA (miR)-155 is a novel gene regulator with important roles in inflammation. Herein,
our study aimed to explore the role of miR-155 in LPS-induced acute lung injury (ALI). ALI in …