Hyperphosphatemia is the most common metabolic complications of end-stage kidney
disease (ESKD). Large observational studies have identified hyperphosphatemia as an …

Hyperphosphatemia is a nearly universal complication of end-stage renal disease that is
widely recognized as one of the most important and most challenging clinical targets to meet …

The kidney plays a central role in the maintenance of phosphorus homeostasis. Thus
disturbance of phosphorus metabolism develops in most patients with chronic kidney …

Rationale & Objective Hyperphosphatemia is a risk factor for poor clinical outcomes in
patients with kidney failure receiving maintenance dialysis. Opinion-based clinical practice …

Hyperphosphatemia is a characteristic feature of chronic kidney disease-mineral and bone
disorder (CKD-MBD). Phosphorus excess is an independent risk factor for cardiovascular …

Hyperphosphatemia is a characteristic complication of significant chronic kidney disease.
Elevated serum phosphorous is associated with reduced survival. Hyperphosphatemia has …

Population-based studies have shown that most patients with advanced chronic kidney
disease (CKD) do not have optimal phosphate levels. Meta-analyses suggest that there is a …

Treatment of hyperphosphatemia in patients with chronic kidney disease on maintenance
hemodialysis: Results of the CARE study. Most patients with end-stage renal disease …

In advanced renal disease, the kidney is unable to maintain phosphate balance due to
decreased urinary excretion as well as the imbalance of the bone metabolic axis. It is well …

Hyperphosphatemia eventually develops in almost all patients with advanced chronic
kidney disease and is associated with negative clinical outcomes. Thus, guidelines …