Nitrogen-rich heterocycles, particularly quinazolines and quinazolinones, represent a
unique class of diversified frameworks displaying a broad spectrum of biological functions …

The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Drug development has been a principal driving force in the rapid maturation of the field of
medicinal chemistry during the past several decades. During this period, the intriguing and …

Introduction: Quinazoline and quinazolinone scaffolds represent an important class of
biologically active nitrogen heterocyclic compounds. A variety of marketed drugs are based …

In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines,
possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV …

Conclusions Given the advances in synthetic methodology and technology in recent years
and the continued interest in the quinazoline skeleton in medicinal chemistry and drug …

Most of the drugs and pharmacologically relevant molecules possess heterocyclic ring
structures and presence of hetero atoms or groupings divulges privileged specificities in …

2, 3-Dihydroquinazolin-4-one (DHQ) belongs to the class of nitrogen-containing heterocyclic
compounds representing a core structural component in various biologically active …

Privileged structures can bind to a diverse range of targets with high affinities, thus
benefiting the discovery of novel bioactive agents. 8-Hydroxyquinoline derivatives represent …

Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …