The plasminogen (Plg)/plasmin (Pla) system is associated with a variety of biological
activities beyond the classical dissolution of fibrin clots, including cell migration, tissue …

Abstract The Plasminogen/Plasmin (Plg/Pla) system, best known for its classical role in
thrombolysis, has been recently highlighted as a regulator of other biological processes in …

Plasminogen (PLG) is the zymogen of plasmin, the major enzyme that degrades fibrin clots.
In addition to its binding and activation on fibrin clots, PLG also specifically interacts with cell …

Inflammation resolution is an active process that functions to restore tissue homeostasis.
Clearance of apoptotic leukocytes by efferocytosis at inflammatory sites plays an important …

Localization of plasmin on macrophages and activation of pro–MMP-9 play key roles in
macrophage recruitment in the inflammatory response. These functions are promoted by …

Inflammation resolution is an active process that functions to restore tissue homeostasis. The
participation of the plasminogen (Plg)/plasmin (Pla) system in the productive phase of …

Review of the available evidence for physiological and pathophysiological roles of the
serine protease plasmin in inflammatory processes. The serine protease plasmin generated …

It is widely held that the plasminogen (Plg) system plays a role in inflammation through
plasmin-mediated directional cell migration. However, substantial evidence for its …

Inflammation plays a critical role in the development of cardiovascular diseases. Infiltration
of leukocytes to sites of injury requires their exit from the blood and migration across …

The interaction of plasminogen with cell surfaces results in promotion of plasmin formation
and retention on the cell surface. This results in arming cell surfaces with the broad …