Mepolizumab for eosinophilic granulomatosis with polyangiitis: a European multicenter observational study

A Bettiol, ML Urban, L Dagna, V Cottin… - Arthritis & …, 2022 - Wiley Online Library
Objective Mepolizumab proved to be an efficacious treatment for eosinophilic
granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the …

[HTML][HTML] Mepolizumab or placebo for eosinophilic granulomatosis with polyangiitis

ME Wechsler, P Akuthota, D Jayne… - … England Journal of …, 2017 - Mass Medical Soc
Background Eosinophilic granulomatosis with polyangiitis is an eosinophilic vasculitis.
Mepolizumab, an anti–interleukin-5 monoclonal antibody, reduces blood eosinophil counts …

[HTML][HTML] Evaluation of clinical benefit from treatment with mepolizumab for patients with eosinophilic granulomatosis with polyangiitis

J Steinfeld, ES Bradford, J Brown, S Mallett… - Journal of Allergy and …, 2019 - Elsevier
Background In a recent phase III trial (NCT02020889) 53% of mepolizumab-treated versus
19% of placebo-treated patients with eosinophilic granulomatosis with polyangiitis (EGPA) …

[HTML][HTML] Effectiveness and safety of anti-IL-5/Rα biologics in eosinophilic granulomatosis with polyangiitis: a two-year multicenter observational study

S Nolasco, A Portacci, R Campisi… - Frontiers in …, 2023 - frontiersin.org
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare vasculitis
characterized by asthma, systemic manifestations, and blood and tissue eosinophilia …

Use of biologics to treat relapsing and/or refractory eosinophilic granulomatosis with polyangiitis: data from a European collaborative study

A Canzian, N Venhoff, ML Urban… - Arthritis & …, 2021 - Wiley Online Library
Objective To describe the efficacy and safety of biologics for the treatment of eosinophilic
granulomatosis with polyangiitis (EGPA). Methods A retrospective European collaborative …

Efficacy and safety of reslizumab in the treatment of eosinophilic granulomatosis with polyangiitis

LA Manka, VP Guntur, JL Denson, RM Dunn… - Annals of Allergy …, 2021 - Elsevier
Background Eosinophilic granulomatosis with polyangiitis (EGPA), a rare vasculitis with
substantial morbidity, is characterized by asthma, eosinophilia, sinusitis, pulmonary …

Benralizumab as a steroid-sparing treatment option in eosinophilic granulomatosis with polyangiitis

VP Guntur, LA Manka, JL Denson, RM Dunn… - The Journal of Allergy …, 2021 - Elsevier
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a vasculitis associated
with significant morbidity and mortality that has historically been treated with systemic …

Anti‐IgE monoclonal antibody (omalizumab) in refractory and relapsing eosinophilic granulomatosis with polyangiitis (Churg‐Strauss): data on seventeen patients

M Jachiet, M Samson, V Cottin, JE Kahn… - Arthritis & …, 2016 - Wiley Online Library
Objective To describe the efficacy and safety of omalizumab, an anti‐IgE monoclonal
antibody, in patients with refractory and/or relapsing eosinophilic granulomatosis with …

Benralizumab versus Mepolizumab for Eosinophilic Granulomatosis with Polyangiitis

ME Wechsler, P Nair, B Terrier, B Walz… - … England Journal of …, 2024 - Mass Medical Soc
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a vasculitis
characterized by eosinophilic inflammation. Benralizumab, a monoclonal antibody against …

Efficacy and safety of rituximab in the treatment of eosinophilic granulomatosis with polyangiitis

V Teixeira, AJ Mohammad, RB Jones, R Smith… - RMD open, 2019 - rmdopen.bmj.com
Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is a subset of
antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis with distinct …