Methacholine inhalation tests are used to help in the diagnosis of asthma when spirometry is
normal. However, the significance of increased methacholine responsiveness in patients …

In order to study whether the methacholine inhalation challenge could predict which patients
with allergic rhinitis were at risk to develop asthma, we prospectively studied a group of …

Methacholine tests are widely used as a diagnostic aid for asthma. Their strength has been
reputed to be the high sensitivity and very infrequent occurrence of false-negative test …

A standardized bronchial histamine challenge was performed in 423 patients presenting
with 1) asthma, 2) rhinitis, 3) asthma and rhinitis 4) rhinitis with cough or 5) chronic cough …

The response to inhaled methacholine is increased in patients with chronic airflow
obstruction, but it is not known whether this is due to true hyperresponsiveness or is a result …

Bronchial responsiveness is the term used to de-scribe the tendency of the airways to
bronchoconstrict to specific stimuli such as allergens and isocyanates, which select a limited …

To determine the predictive value of wheeze compared to methacholine inhalation
challenge (MIC) in diagnosing asthma, we prospectively evaluated 34 patients considered …

Distribution of bronchial hyperresponsiveness to methacholine was assessed in 791
consecutive patients who were referred to the outpatient clinic of the pulmonary department …

The frequency with which disagreement occurs between the clinician's diagnosis of asthma
and the objective measurement of methacholine airway responsiveness is not known. We …

A screening test to measure nonspecific airways reactivity was developed and compared to
a standard methacholine inhalation challenge in 13 asthmatic patients and ten normal …