The influence of fenofibrate on lipid profile, endothelial dysfunction, and inflammatory markers in type 2 diabetes mellitus patients with typical and mixed dyslipidemia
Background Type 2 diabetes is associated with early development of endothelial
dysfunction. Patients present with typical dyslipidemia (predominantly high levels of …
dysfunction. Patients present with typical dyslipidemia (predominantly high levels of …
Decrease in inflammatory cardiovascular risk markers in hyperlipidemic diabetic patients treated with fenofibrate
TJ Wu, HY Ou, CW Chou, SH Hsiao… - Annals of Clinical & …, 2007 - Assoc Clin Scientists
The goal was to investigate the effect of micronized fenofibrate, a hypolipidemic drug, on
inflammatory markers and proinsulin in patients with type 2 diabetes who had …
inflammatory markers and proinsulin in patients with type 2 diabetes who had …
Fenofibrate: a review of its lipid-modifying effects in dyslipidemia and its vascular effects in type 2 diabetes mellitus
GM Keating - American Journal of Cardiovascular Drugs, 2011 - Springer
Fenofibrate is a fibric acid derivative with lipid-modifying effects that are mediated by the
activation of peroxisome proliferator-activated receptor-α. Fenofibrate also has a number of …
activation of peroxisome proliferator-activated receptor-α. Fenofibrate also has a number of …
Fenofibrate effects on arterial endothelial function in adults with type 2 diabetes mellitus: a FIELD substudy
JA Harmer, AC Keech, AS Veillard, MR Skilton… - Atherosclerosis, 2015 - Elsevier
Objective Dislipidaemia in type 2 diabetes mellitus contributes to arterial endothelial
dysfunction and an increased risk of cardiovascular disease. Fenofibrate, a lipid-regulating …
dysfunction and an increased risk of cardiovascular disease. Fenofibrate, a lipid-regulating …
Fenofibrate, simvastatin and their combination in the management of dyslipidaemia in type 2 diabetic patients
G Derosa, P Maffioli, SAT Salvadeo… - … medical research and …, 2009 - Taylor & Francis
Objective: To evaluate the efficacy of fenofibrate, simvastatin or their combination in type 2
diabetic patients with combined dyslipidaemia. Research design and methods: 241 patients …
diabetic patients with combined dyslipidaemia. Research design and methods: 241 patients …
Fenofibrate improves endothelial function and plasma myeloperoxidase in patients with type 2 diabetes mellitus: an open-label interventional study
C Nita, C Bala, M Porojan, N Hancu - Diabetology & metabolic syndrome, 2014 - Springer
Background Fenofibrate offers a number of benefits on the cardiovascular system and it is
plausible that its anti-inflammatory, anti-oxidant and anti-fibrotic effects and enhancement of …
plausible that its anti-inflammatory, anti-oxidant and anti-fibrotic effects and enhancement of …
Fenofibrate improves endothelial function in the brachial artery and forearm resistance arterioles of statin-treated Type 2 diabetic patients
SJ Hamilton, GT Chew, TME Davis, GF Watts - Clinical science, 2010 - portlandpress.com
Dyslipidaemia contributes to endothelial dysfunction and CVD (cardiovascular disease) in
Type 2 diabetes mellitus. While statin therapy reduces CVD in these patients, residual risk …
Type 2 diabetes mellitus. While statin therapy reduces CVD in these patients, residual risk …
Micronized fenofibrate normalizes the enhanced lipidemic response to a fat load in patients with type 2 diabetes and optimal glucose control
E Cavallero, C Dachet, F Assadolahi, C Martin… - Atherosclerosis, 2003 - Elsevier
This study evaluated the postprandial (PP) response to an oral fat load in 28 male patients
with type 2 diabetes (mean HbA1c of 5.1%), all receiving metformin and performing physical …
with type 2 diabetes (mean HbA1c of 5.1%), all receiving metformin and performing physical …
Favourable effects of fenofibrate on lipids and cardiovascular disease in women with type 2 diabetes: results from the Fenofibrate Intervention and Event Lowering in …
MC d'Emden, AJ Jenkins, L Li, D Zannino, KP Mann… - Diabetologia, 2014 - Springer
Aims/hypothesis In the double-blind placebo-controlled Fenofibrate Intervention and Event
Lowering in Diabetes trial (n= 9,795), fenofibrate reduced major cardiovascular events in …
Lowering in Diabetes trial (n= 9,795), fenofibrate reduced major cardiovascular events in …
Effects of fenofibrate on endothelial function and cell adhesion molecules during post‐prandial lipemia in hypertriglyceridemia
S Marchesi, G Lupattelli, R Lombardini… - Journal of clinical …, 2003 - Wiley Online Library
Background: Fasting and post‐prandial hypertriglyceridemia have been associated with
endothelial dysfunction. Objective: To investigate the effects of a 3‐month treatment with …
endothelial dysfunction. Objective: To investigate the effects of a 3‐month treatment with …
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