Efficacy and safety of immunotherapy in elderly patients with non-small cell lung cancer

G Galli, A De Toma, F Pagani, G Randon, B Trevisan… - Lung Cancer, 2019 - Elsevier
Abstract Objectives Most trials with Immune Checkpoint Inhibitors (ICIs) for Non-Small Cell
Lung Cancer (NSCLC) included only small subgroups of patients aged≥ 65. As NSCLC is …

[HTML][HTML] Immunotherapy in the first-line treatment of elderly patients with advanced non-small-cell lung cancer: results of an International Experts Panel Meeting by the …

C Gridelli, S Peters, V Velcheti, I Attili, F De Marinis - ESMO open, 2023 - Elsevier
Background The use of immune checkpoint inhibitors (ICIs) in the front-line treatment of
advanced non-small-cell lung cancer (NSCLC) is currently the standard of care. However …

Efficacy and safety of immune checkpoint inhibitor monotherapy in pretreated elderly patients with non-small cell lung cancer

O Yamaguchi, H Imai, H Minemura, K Suzuki… - Cancer Chemotherapy …, 2020 - Springer
Abstract Purpose Immune checkpoint inhibitors (ICIs) are an effective subsequent-line
treatment for patients with advanced non-small cell lung cancer (NSCLC). However, it …

Real‐world data on the efficacy and safety of immune‐checkpoint inhibitors in elderly patients with non‐small cell lung cancer

D Morinaga, H Asahina, S Ito, O Honjo… - Cancer …, 2023 - Wiley Online Library
Abstract Purpose Immune‐checkpoint inhibitors (ICIs) are effective against advanced non‐
small cell lung cancer (NSCLC). However, whether the efficacy and safety of ICI treatment in …

Immunotherapy or chemoimmunotherapy in older adults with advanced non–small cell lung cancer

Y Tsukita, T Tozuka, K Kushiro, S Hosokawa… - JAMA …, 2024 - jamanetwork.com
Importance Immune checkpoint inhibitor (ICI) plus chemotherapy combination treatment (ICI-
chemotherapy) is now a standard treatment for non–small cell lung cancer (NSCLC) without …

Immune checkpoint inhibitors in real‐world treatment of older adults with non–small cell lung cancer

E Muchnik, KP Loh, M Strawderman… - Journal of the …, 2019 - Wiley Online Library
OBJECTIVE To evaluate the efficacy and toxicity of immune checkpoint inhibitors (ICIs) in
older patients with advanced non–small cell lung cancer (NSCLC) seen in routine clinical …

[HTML][HTML] Clinical efficacy of immune checkpoint inhibitors in older non-small-cell lung cancer patients: a meta-analysis

YM Sun, Y Wang, XX Sun, J Chen, ZP Gong… - Frontiers in …, 2020 - frontiersin.org
Background: Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape
among non-small-cell lung cancer (NSCLC) patients. The efficacy of ICI therapy in older …

[HTML][HTML] Immunotherapy in elderly patients affected by non-small cell lung cancer: a narrative review

M Montrone, G Rosati, V Longo, A Catino… - Journal of Clinical …, 2023 - mdpi.com
Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung
cancer (NSCLC) accounts for approximately 80% of all lung cancers, and most NSCLC is …

Real‐world use and survival outcomes of immune checkpoint inhibitors in older adults with non–small cell lung cancer

B Youn, NA Trikalinos, V Mor, IB Wilson, IJ Dahabreh - Cancer, 2020 - Wiley Online Library
Background Limited data exist regarding the characteristics and survival outcomes of older
adults with non–small cell lung cancer (NSCLC) who receive immune checkpoint inhibitors …

[HTML][HTML] Impact of age on the efficacy of immune checkpoint inhibitor-based combination therapy for non-small-cell lung cancer: a systematic review and meta-analysis

X Yan, X Tian, Z Wu, W Han - Frontiers in oncology, 2020 - frontiersin.org
Background: Despite the acknowledged benefits of immune checkpoint inhibitor (ICI)-based
combination therapy (either with other checkpoint inhibitors, chemotherapy, targeted …