The role of bile acids in metabolic regulation

L Vítek, M Haluzík - Journal of endocrinology, 2016 - joe.bioscientifica.com
Bile acids (BA), long believed to only have lipid-digestive functions, have emerged as novel
metabolic modulators. They have important endocrine effects through multiple cytoplasmic …

[HTML][HTML] Metabolic effects of bile acids: potential role in bariatric surgery

CR Flynn, VL Albaugh, NN Abumrad - Cellular and Molecular …, 2019 - Elsevier
Bariatric surgery is the most effective and durable treatment for morbid obesity, with an
unexplained yet beneficial side effect of restoring insulin sensitivity and improving glycemia …

Bile acids in glucose metabolism in health and disease

H Shapiro, AA Kolodziejczyk, D Halstuch… - Journal of Experimental …, 2018 - rupress.org
Bile acids (BAs) are cholesterol-derived metabolites that facilitate the intestinal absorption
and transport of dietary lipids. Recently, BAs also emerged as pivotal signaling molecules …

The role of bile acids in glucose metabolism and their relation with diabetes

JA González-Regueiro, L Moreno-Castañeda… - Annals of …, 2018 - medigraphic.com
Bile acids (BAs), the end products of cholesterol catabolism, are essential for the absorption
of lipids and fat-soluble vitamins; but they have also emerged as novel signaling molecules …

Endocrine functions of bile acids

SM Houten, M Watanabe, J Auwerx - The EMBO journal, 2006 - embopress.org
Bile acids (BAs), a group of structurally diverse molecules that are primarily synthesized in
the liver from cholesterol, are the chief components of bile. Besides their well‐established …

Increased bile acid synthesis and impaired bile acid transport in human obesity

RA Haeusler, S Camastra, M Nannipieri… - The Journal of …, 2016 - academic.oup.com
Context: Alterations in bile acid (BA) synthesis and transport have the potential to affect
multiple metabolic pathways in the pathophysiology of obesity. Objective: The objective of …

Bile acid physiology

A Di Ciaula, G Garruti, RL Baccetto… - Annals of …, 2018 - medigraphic.com
The primary bile acids (BAs) are synthetized from cholesterol in the liver, conjugated to
glycine or taurine to increase their solubility, secreted into bile, concentrated in the …

Bile acids and bariatric surgery

VL Albaugh, B Banan, H Ajouz, NN Abumrad… - Molecular aspects of …, 2017 - Elsevier
Bariatric surgery, specifically Roux-en-Y gastric bypass (RYGB) and vertical sleeve
gastrectomy (VSG), are the most effective and durable treatments for morbid obesity and …

Bile acids, obesity, and the metabolic syndrome

H Ma, ME Patti - Best practice & research Clinical gastroenterology, 2014 - Elsevier
Bile acids are increasingly recognized as key regulators of systemic metabolism. While bile
acids have long been known to play important and direct roles in nutrient absorption, bile …

Bile acids in glucose metabolism and insulin signalling—mechanisms and research needs

TR Ahmad, RA Haeusler - Nature Reviews Endocrinology, 2019 - nature.com
Of all the novel glucoregulatory molecules discovered in the past 20 years, bile acids (BAs)
are notable for the fact that they were hiding in plain sight. BAs were well known for their …