This article provides an overview of the research, beginning a century ago, that has led to
the current use of genomically informed methods for selection of targeted therapies to treat …

Personalized cancer medicine is based on increased knowledge of the cancer mutation
repertoire and availability of agents that target altered genes or pathways. Given advances …

Recent advances in tumor genetics and drug development have led to the generation of a
wealth of anticancer targeted therapies. A few recent examples indicate that these drugs are …

Personalised management of cancer means the prescription of specific therapeutics that are
best suited for an individual patient and the type of tumour. Molecular diagnostics influences …

The future of cancer care and treatment lies in the concept of ''personalized medicine,''a
model that focuses on the individual, not just the disease. Personalized medicine in cancer …

Many experts agree that personalized cancer medicine, defined here as treatment based on
the molecular characteristics of a tumor from an individual patient, has great potential in the …

Cancer is one of the leading causes of death in the United States, and more than 1.5 million
new cases and more than 0.5 million deaths were reported during 2010 in the United States …

Medical oncology is rapidly evolving with the implementation of personalized, targeted
therapies. Advances in molecular diagnostics and the biologic understanding of cancer …

Personalized cancer therapy is based on the precept that detailed molecular
characterization of the patient's tumour and its microenvironment will enable tailored …

The utilization of genomic data to direct treatment for cancer patients represents the central
tenet in precision oncology, in which a patient is matched to a specific drug or therapy based …