Carbapenem resistance in Gram-negative bacteria has come into sight as a serious global
threat. Carbapenem-resistant Gram-negative pathogens and their main representatives …

The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …

Antimicrobial resistance represents a serious threat for global health, causing an
unacceptable burden in terms of morbidity, mortality and healthcare costs. In particular, in …

Bacterial infections are a frequent cause of hospitalization, and nosocomial infections are an
increasingly common condition, particularly within the acute/critical care setting. Infection …

Background Healthcare-associated infections involving Gram-negative bacteria (GNB) with
difficult-to-treat resistance (DTR) phenotype are associated with impaired patient-centered …

Introduction: Not enough data exist to inform the optimal duration and type of antimicrobial
therapy against GN infections in critically ill patients. Methods: Narrative review based on a …

Infections due to carbapenem-resistant Gram-negative bacteria are burdened by high
mortality and represent an urgent threat to address. Clinicians are currently at a dawn of a …

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Infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …

The global spread of carbapenem-resistant Enterobacteriaceae (CRE) is increasingly
becoming a major challenge in clinical and public health settings. To date, the treatment for …