Fixed‐dose combinations (FDC) have been developed to reduce the pill burden for
hypertensive patients. Data on fixed‐dose or free‐dose (freeDC) ramipril/amlodipine (R/A) …

BACKGROUND:: Patients with hypertension may require combination therapy to attain the
blood pressure targets recommended by US and European treatment guidelines …

Abstract▴ Amlodipine, a dihydropyridine calcium channel blocker, and valsartan, an
angiotensin II receptor blocker, are established antihypertensive agents. Fixed-dose …

This community-based study assessed whether there were age, sex, or racial differences in
response to amlodipine 5 to 10 mg once daily in patients with mild to moderate essential …

Objective: To investigate whether a proactive multifactorial risk factor intervention strategy
using single-pill amlodipine/atorvastatin (5/10, 10/10 mg) in addition to other …

Objectives: An international double-blind, parallel-group, randomized controlled trial was
performed to determine the efficacy and safety of a new first-line strategy in mild to moderate …

BACKGROUND: Hypertension guidelines recommend the use of 2 agents with synergistic
action when> 1 agent is needed to achieve blood pressure goals. Newer antihypertensive …

Systolic hypertension is predominant among patients over 50 years of age, is a more
important cardiovascular risk factor than diastolic blood pressure, and is more difficult to …

The objective of this review is to evaluate the role of fixed-dose triple-combination therapy
for the management of hypertension. An assessment of clinical trials showed that half the …

Hypertension is a major modifiable risk for the development of cardiovascular,
cerebrovascular and renal diseases. Thus, effective treatment of high blood pressure is an …