[HTML][HTML] A randomized trial of the effects of atorvastatin and niacin in patients with combined hyperlipidemia or isolated hypertriglyceridemia

S Weiss, S Kafonek, DM Black… - The American journal of …, 1998 - Elsevier
Background: To assess the lipid-lowering effects and safety of atorvastatin and niacin in
patients with combined hyperlipidemia or isolated hypertriglyceridemia. Methods: We …

Long-term persistence with single-pill, fixed-dose combination therapy versus two pills of amlodipine and perindopril for hypertension: Australian experience

LA Simons, E Chung, M Ortiz - Current medical research and …, 2017 - Taylor & Francis
Objective: To study treatment persistence and mortality using a single-pill, fixed-dose
combination tablet compared with a two-pill combination for hypertension. Research design …

Fixed-dose combination therapy in hypertension: cons

F Angeli, G Reboldi, G Mazzotta, M Garofoli… - High Blood Pressure & …, 2012 - Springer
The goal of antihypertensive therapy is to reduce the risk associated with blood pressure
elevation. Although the choice of first-line drug therapy may exert some effects on different …

[HTML][HTML] A practical approach to switch from a multiple pill therapeutic strategy to a polypill-based strategy for cardiovascular prevention in patients with hypertension

A Coca, R Kreutz, AJ Manolis, G Mancia - Journal of hypertension, 2020 - journals.lww.com
Pharmacological treatment recommended by guidelines for very high-risk patients with
established cardiovascular disease (CVD) includes lipid-lowering drugs, antihypertensive …

Effects of simvastatin (40 and 80 mg/day) in patients with mixed hyperlipidemia

E Stein, D Plotkin, H Bays, M Davidson… - The American journal of …, 2000 - Elsevier
Mixed hyperlipidemia is characterized by both elevated total cholesterol and triglycerides. It
is estimated to account for 10% to 20% of patients with dyslipidemia. This study assessed …

A pilot double‐blind randomised placebo‐controlled trial of the effects of fixed‐dose combination therapy ('polypill') on cardiovascular risk factors

F Malekzadeh, T Marshall, A Pourshams… - … journal of clinical …, 2010 - Wiley Online Library
Aim: Our objective was to investigate the effects and tolerability of fixed‐dose combination
therapy on blood pressure and LDL in adults without elevated blood pressure or lipid levels …

Triple combination therapy for global cardiovascular risk: atorvastatin, perindopril, and amlodipine

ME Bertrand, C Vlachopoulos, JJ Mourad - American Journal of …, 2016 - Springer
Statins, angiotensin-converting enzyme (ACE) inhibitors, and calcium channel blockers
(CCBs) have markedly changed the clinical progression of patients with coronary artery …

Multicenter placebo-controlled comparison of amlodipine and atenolol in mild to moderate hypertension

B De Bruijn, G Cocco, HM Tyler - Journal of Cardiovascular …, 1988 - journals.lww.com
Once-daily administration of amlodipine, a long-acting dihydropyridine calcium-channel
blocker, and atenolol, a cardioselective [beta]-adrenoceptor blocking agent, were compared …

Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension

JF Burris, RP Ames, WB Applegate… - Journal of …, 1988 - journals.lww.com
Amlodipine, a new long-acting dihydropyridine calcium antagonist, was compared with
hydrochlorothiazide (HCTZ) in 145 patients with mild to moderate hypertension. After 4 …

Prevalence, treatment, and control of combined hypertension and hypercholesterolemia in the United States

ND Wong, V Lopez, S Tang, GR Williams - The American journal of …, 2006 - Elsevier
Hypertension and hypercholesterolemia are important modifiable risk factors for
cardiovascular disease (CVD). We examined the prevalence, treatment, and control of …