Aims Estrogen plays an important role in cardioprotection. Animal experiments showed that
the G-protein coupled estrogen receptor 30 (GPR30) specific agonist G1 could reduce post …

BACKGROUND: Estrogen may protect against the development of cardiovascular disease.
Recently, a receptor known as GPR30 that seems to mediate estrogen's nongenomic effects …

Premenopausal women have a reduced risk for cardiovascular disease. Estrogen deficiency
augments cardiac inflammation and oxidative stress and, thereby, aggravates myocardial …

Several studies have recently demonstrated that G protein‑coupled estrogen receptor
(GPER) 30 directly binds to estrogen and mediates its action. The aim of the present study …

The incidence of left ventricular diastolic dysfunction significantly increases in
postmenopausal women suggesting the association between estrogen loss and diastolic …

The incidence of cardiovascular diseases was significantly increased in postmenopausal
women. The protection of estrogen in the cardiovascular system has been further reported …

G-protein coupled estrogen receptor 1, GPER, formerly known as GPR30, is a seven
transmembrane domain receptor that mediates rapid estrogen responses in a wide variety of …

Premenopausal females have a lower incidence of cardiovascular disease than their male
counterparts, but the mechanism is unclear. Estrogen has been thought to signal through …

Three types of estrogen receptors (ER) exist in the heart, Esr1, Esr2 and the G protein-
coupled estrogen receptor 1, Gper1. However, their relative importance in mediating …

Aims GPR30 is a novel oestrogen receptor expressed in various tissues, including the heart.
We determined the role of GPR30 in the maintenance of left ventricular (LV) structure and …