Background This study explores the protective effects of a hydrogen sulfide donor,
morpholin-4-ium 4-methoxyphenyl-morpholino-phosphinodithioate (GYY4137), in the hearts …

The molecular mechanisms of postmenopausal heart diseases in women may involve the
loss of estrogen-deactivation of its membrane receptor, G-protein coupled estrogen receptor …

The proliferation and apoptosis of cells in the placenta play a critical role in preeclampsia
(PE) in which estrogen has been implicated via estrogen receptors (ERs). A novel ER, G …

Ischemic heart disease is one of the most common diseases in modern society. Ischemic
myocardium can be salvaged by vascular recanalization therapy, but its benefit is attenuated …

Background The initiation of atherosclerosis (AS) is attributed to the dysfunction of
endothelial cells (ECs) via the inhibition of g protein-coupled estrogen receptor (GPER). In …

Although female protection from cardiovascular diseases declines with the fall in circulating
sex hormones experienced during menopause, clinical trials in older women fail to …

While classical cannabinoid receptors are known to crucially impact on myocardial infarction
(MI) repair, a function of the cannabinoid-sensitive receptor GPR55 herein is poorly …

The G Protein-Coupled Estrogen Receptor (GPER) is a novel membrane-bound receptor
that mediates non-genomic actions of the primary female sex hormone 17β-estradiol …

Stress-induced cardiovascular diseases characterized by inflammation are among the
leading causes of morbidity and mortality in postmenopausal women worldwide. Estradiol …

Endogenous estrogens protect from coronary artery disease in premenopausal women, but
the mechanisms involved are only partly understood. This study investigated whether …